Abstract

Background: The demographic pattern and the trend of disease (dengue fever) are
largely changing everyyear through the past decade.Early recognition and prompt
initiation of appropriate management is vital. The aim of this study to correlate the
clinical profile with laboratory investigations and radiological findings in dengue fever
at tertiary care center.
Materials& Methods: A cross sectional study done on 50 children less than 12 years of
age with clinical signs and symptoms of Dengue- any acute febrile illness in department
of Pediatrics, RUHS College of Medical Sciences, Jaipur, Rajasthan, India during one
year period. For all suspected dengue fever, the IgM ELISA qualitative test was done at
our hospital. Children positive for IgM dengue were taken up for study and followed up
for clinical profile.Labinvestigations carried out in these patients include CBC,
Haemoglobin, renal functiontest, Liver function test and Dengue IgM serology. Chest X
ray was taken todemonstrate pleural effusion. Children positive for IgM were followed
up for the clinicalprofile and outcome.
Results: Our study showed that the larger number of cases was in 6 to 12 years.).Males
were affected slightly more than females in total and also insubgroupsexceptin DHF
III.Itwas not significant (P>0.05).The mean duration of fever was 6.23 days.Pleural
effusion was seen 6 patients, of which more cases in dengue feverwith warning sign.
Abdominal tenderness was seen in 46% of cases, highest in denguefever with warning
signs and lowest in mild dengue which is statistically significant.Ascites was seen in 20
% of cases, highest in dengue fever with warning signs andDHF IV. Hepatomegaly was
seen in 30%, highest in DHF IV and lowest in mild dengue which is statistically
significant. The splenomegaly was seen in 4% of cases. AST was elevated in 36% of
cases. More in DHFIII & DHFIV cases, but it is not statistically significant. ALT was
increased in 30% of cases. More elevated cases are in DHFIII which was also not
significant.