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Haematological parameters in type 2 diabetes mellitus, controlled and uncontrolled

    Author

    • Akhouri Sukrit Prakash
,

Document Type : Research Article

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Abstract

Aims: To compare HbA1c levels with inflammatory markers that include a neutrophilto-
lymphocyte ratio (NLR) and monocyteto-lymphocyte ratio (MLR) in controlled and
uncontrolled diabetics.
Materials and methods: Two hundred type 2 diabetes mellitus (T2DM) patients were
separated into two groups of managed (HbA1c 7%) diabetics. HbA1c (glycated
haemoglobin) levels, leukocyte count (WBC), haemoglobin (Hb), hematocrit (Hct), red
blood cell distribution width (RDW), neutrophils, lymphocytes, and monocytes were all
measured using recent laboratory data. The laboratory results were used to determine
the NLR and MLR.
Results:Controlled diabetics had a mean age of 58.30 years, while uncontrolled diabetics
had a mean age of 55.62 years. The mean NLR in diabetics with and without diabetes
was 2.61 and 4.88, respectively. The distinction was discovered to be statistically
significant (p < 0.05). The mean MLR in diabetics with and without diabetes was 0.2
and 0.24, respectively, however the difference was not statistically significant (p > 0.05).
The data showed a modest positive connection between HbA1c levels and the
haematological indices, but it was statistically insignificant.
Conclusion: The study found a substantial difference in NLR between diabetics who
were well-controlled and those who were not. Although only a slight positive connection
was detected between glycated Hb levels and the haematological indices, the results
revealed a substantial difference in NLR between the two groups. This demonstrates
that these ratios have the potential to be used as inflammatory indicators in T2DM.

Keywords

  • Diabetes
  • diabetes mellitus
  • Hematological indices
  • Inflammation
  • inflammatory markers
  • Microvascular complications
  • Monocyteto-lymphocyte ratio
  • neutrophil-to-lymphocyte ratio
  • Type 2 Diabetes mellitus
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European Journal of Molecular & Clinical Medicine
Volume 9, Issue 3
February 2022
Page 10078-10084
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  • Article View: 166
  • PDF Download: 358

APA

Prakash, A. S. (2022). Haematological parameters in type 2 diabetes mellitus, controlled and uncontrolled. European Journal of Molecular & Clinical Medicine, 9(3), 10078-10084.

MLA

Akhouri Sukrit Prakash. "Haematological parameters in type 2 diabetes mellitus, controlled and uncontrolled". European Journal of Molecular & Clinical Medicine, 9, 3, 2022, 10078-10084.

HARVARD

Prakash, A. S. (2022). 'Haematological parameters in type 2 diabetes mellitus, controlled and uncontrolled', European Journal of Molecular & Clinical Medicine, 9(3), pp. 10078-10084.

VANCOUVER

Prakash, A. S. Haematological parameters in type 2 diabetes mellitus, controlled and uncontrolled. European Journal of Molecular & Clinical Medicine, 2022; 9(3): 10078-10084.

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