Abstract

Background: Laparoscopic surgery has rapidly gained wide spread acceptance for the
last couple of decades, yet it is marred with the occurrence of post-operative port site
infections. One of the better ways of tackling port site infection is its prevention. Hence
the present study was conducted to compare the efficacy of single dose antibiotic
prophylaxis vis conventional multidose antibiotic therapy in patients of low risk elective
laparoscopic cholecystectomy.
Materials and Methods: The patients were divided in two groups, Group A and Group
B with 34 and 36 patients respectively. Patients were assessed for any post-operative
fever at frequent intervals for 24-48 hours and noted down and port sites were assessed
for any induration, discharge, erythema or tenderness.
Results: The age of the patients ranged from 19-55 years and 15-55 years in group A
and group B respectively. Three patients in each group developed low grade fever in the
post-operative period (day 1) that settled with paracetamol and didn’t merit further
evaluation. Two patients developed port site discharge with mild gaping at the
epigastric port site in group A. One patient developed port site discharge in group B.
The difference was statistically insignificant.
Conclusion: Hence, it is concluded that the efficacy of the single dose antibiotic
prophylaxis is the same as the conventional multiple dose antibiotic prophylaxis
therapy.