Abstract

Background:Chronic kidney disease (CKD) is a devastating medical, social, and economic
problem for patients and their families.The present study correlated findings in pulmonary
function test with stages of chronic kidney disease.
Materials & Methods:100 confirmed cases of CKD and 40 controls were included.
Standard spirometric pulmonary function tests were performed immediately before and after
the midweek hemodialysis session.
Results: Most common age group was 31-40 years [34 (34%)] followed by 21-30years [17
(17%)] and 41-50 years [16 (16%)].Most commonly observed PFT pattern was Mild
restrictive [22 (22%)] followed by moderate restrictive [19 (19%)]. 25 patients with mild
restrictive pattern, 13 (52%)belong to stage 3, 5 (20%) belong to stage 4, 6 (24%) belong to
stage 2 and 1 (4%) belong to stage 5 CKD whereas, out of 19 patients with moderate
restrictive pattern, 9 (47.36%) belong to stage 5 and 5 (26.31%) each belong to stage 2 and 3
respectively. Out of 12 patients with moderately severe restrictive pattern 6 (50%) in each
belong to stage 4 and 5 respectively. All two severe restrictive pattern patients belong to stage
5 CKD.
Conclusion: In CKD patients there exists a significant pulmonary morbidity in restrictive
pattern. This restrictive abnormality depends on stage of CKD and worsens as the CKD stage
worsens. Most common finding was mild restrictive pattern suggesting that clinically patient
may not get debilitating symptoms due to this.