• Register
  • Login

European Journal of Molecular & Clinical Medicine

  1. Home
  2. Serum Insulin and Atherosclerotic Markers in Acanthosis Nigricans Patients

Current Issue

By Issue

By Author

By Subject

Author Index

Keyword Index

About Journal

Aims and Scope

Editorial Board

Publication Ethics

Indexing and Abstracting

Related Links

FAQ

Peer Review Process

Journal Metrics

News

Serum Insulin and Atherosclerotic Markers in Acanthosis Nigricans Patients

    Author

    • Shravya B, Navaneetha Reddy Pisati, Vijay Bhasker Reddy Ch, Chinnapu Reddy Gopu, Ashok Rao Matety
,

Document Type : Research Article

  • Article Information
  • Download
  • Export Citation
  • Statistics
  • Share

Abstract

Background: To study serum insulin levels and atherosclerotic markers in patients with
acanthosis nigricans in a rural tertiary care center.
Materials and Methods: It was a Cross sectional study. The study was conducted in the
Departments of Biochemistry and Dermatology, Venereology, Leprosy (DVL), at
Kamineni Institute of Medical Sciences, India.
Results: Total number of patients recruited for the study was 50. Mean age of the
patient was 26.8 years. Females (60%) have outnumbered males (40%). Overall
majority of the acanthosis nigricans patients were students (46%). Among females
majority of them were housewives (22%). In a majority of the patients, neck was the
initial site of darkening (82%). Most of them have duration of darkening of skin for
more than one year (64%) and 84% of the patients had an insidious onset. Forty six
percent of patients had associated medical illness such as hypothyroidism (22%),
diabetes mellitus (10%), hypertension (8%), polycystic ovarian syndrome (4%),
psoriasis (2%). Neck(98%) is the most common site of acanthosis nigricans followed by
axilla(88%); elbow(42%); periorbital region(36%); groin(34%); knees(24%);
temples(22%); infralabial region(20%); antecubital fossa(14%); perioral and perinasal
(12% each); knuckles(10%); skin over hyoid bone(8%); sides of waist and
inframammary areas(6% each) and popliteal fossa(2%). Out of 50 patients, raised
serum insulin levels seen in 54% patients, of which 42% are non-diabetics and 12% are
diabetics. Also, 96% had normal fasting blood sugars (FBS <110mg/dL), 80% had
normal postprandial blood sugars (PPBS <140mg/dL). All patients (100%) had normal
total cholesterol (< 250mg/dL), 80% patients had normal HDLc (>35mg/dL), 98% had
normal LDLc (< 130mg/dL), 80% had normal triglycerides (<160mg/dL), 86% had
normal VLDLc < 40mg/dL, out of the total 50 patients with acanthosis nigricans.
Conclusion: Hypothyroidism was present in 22% of the patients with acanthosis
nigricans whereas diabetes mellitus was present in 10% of the patients with acanthosis
nigricans. Levels of fasting serum insulin were raised in 54% of patients having burke’s
neck severity score of 2, 3, 4 and neck texture score of 2,3 and axilla severity score of 2,3
in patients with acanthosis nigricans. About 20% of studied patients had decreased
HDL cholesterol levels(<35 mg/dL and increased serum triglycerides(>160 mg/dL).

Keywords

  • acanthosis nigricans
  • Fasting Insulin
  • Axilla
  • triglycerides
  • Neck severity
  • Popliteal fossa
  • hypothyroidism
  • XML
  • PDF 247.4 K
  • RIS
  • EndNote
  • Mendeley
  • BibTeX
  • APA
  • MLA
  • HARVARD
  • VANCOUVER
    • Article View: 152
    • PDF Download: 171
European Journal of Molecular & Clinical Medicine
Volume 9, Issue 3
February 2022
Page 968-975
Files
  • XML
  • PDF 247.4 K
Share
Export Citation
  • RIS
  • EndNote
  • Mendeley
  • BibTeX
  • APA
  • MLA
  • HARVARD
  • VANCOUVER
Statistics
  • Article View: 152
  • PDF Download: 171

APA

Matety, S. B. N. R. P. V. B. R. C. C. R. G. A. R. (2022). Serum Insulin and Atherosclerotic Markers in Acanthosis Nigricans Patients. European Journal of Molecular & Clinical Medicine, 9(3), 968-975.

MLA

Shravya B, Navaneetha Reddy Pisati, Vijay Bhasker Reddy Ch, Chinnapu Reddy Gopu, Ashok Rao Matety. "Serum Insulin and Atherosclerotic Markers in Acanthosis Nigricans Patients". European Journal of Molecular & Clinical Medicine, 9, 3, 2022, 968-975.

HARVARD

Matety, S. B. N. R. P. V. B. R. C. C. R. G. A. R. (2022). 'Serum Insulin and Atherosclerotic Markers in Acanthosis Nigricans Patients', European Journal of Molecular & Clinical Medicine, 9(3), pp. 968-975.

VANCOUVER

Matety, S. B. N. R. P. V. B. R. C. C. R. G. A. R. Serum Insulin and Atherosclerotic Markers in Acanthosis Nigricans Patients. European Journal of Molecular & Clinical Medicine, 2022; 9(3): 968-975.

  • Home
  • About Journal
  • Editorial Board
  • Submit Manuscript
  • Contact Us
  • Glossary
  • Sitemap

News

 

For Special Issue Proposal : editor.ejmcm21@gmail.com

Newsletter Subscription

Subscribe to the journal newsletter and receive the latest news and updates

© Journal Management System. Powered by ejournalplus