Study of serum lipid profile in patients with oral submucous fibrosis and oral squamous cell carcinoma and their comparative analysis
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 2, Pages 586-592
AbstractAims and Objectives: The aim of the study was to study serum lipid profile and compare
their levels in patients with oral sub mucous fibrosis (OSMF) and oral squamous cell
Materials and Methods: This study was done in two groups of patients ‑ OSMF and OSCC.
There were forty five participants in each group. Serum obtained from centrifugation of 12
hour fasting blood samples was analyzed on fully automated analyzer Beckman coulter AU-
680 for estimating the lipid levels (cholesterol, triglycerides [TGL], and high‑density lipids
[HDL]) by colorimetric method. Low‑density lipid [LDL] values were obtained by calculator.
Results: The comparison of lipid profile between Oral Submucous Fibrosis and Oral
Carcinoma cases shows statistically significant results for TC, HDL and LDL.
Conclusion: The change in lipid levels may have an early diagnostic or prognostic role in
oral premalignant and malignant lesions.
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