To Evaluate Efficacy and Safety of Isobaric Levobupivacaine Versus Hyperbaric Bupivacaine in Lower Limb Orthopaedic Surgeries
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 3, Pages 310-316
Abstract
Background: Neuraxial anaesthesia greatly expand the anaesthesiologistarmamentarium in many cases providing alternative to general anaesthesia. Spinal
anaesthesia is a popular technique for lower limb orthopaedic surgeries. Hyperbaric
bupivacaine in 8% glucose is often used. Unintended intravascular injection of
bupivacaine during regional anaesthesia may cause severe cardiovascular toxicity,
including left ventricular depression,atrioventricular heart block,life threatnig
ventricular tachycardia, fibrillation and sudden cardiac arrest which is difficult to
resuscitate However levobupivacaine has similar efficacy but better safety profile than
racemic bupivacaine.
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