European Journal of Molecular & Clinical Medicine

Abstract

Introduction: Elevation of serum ferritin levels can result in major health issues. Increased oxidative
stress, inflammation, and endothelial damage are all linked to elevated serum ferritin levels, which in
turn raises the risk of hypertension.
Aim: Serum ferritin levels in patients with high blood pressure and a healthy control group were
measured and compared in this study.
Material and Methods: The present study was a hospital-based observational and analytical study. The
study was conducted over a period of 1 year on 60 patients. The study group comprised of 30 patients
(not diagnosed with hypertension or on any treatment) and the control group comprised of 30 (age and
gender matched) individuals. The levels of serum ferritin were analysed by the chemiluminescent
method.
Result: The results of the present study showed that, the mean value of serum ferritin was 313.17 ±
173.86 ng/ml in study group and 169.50 ± 105.66 ng/ml in control group. The mean SBP was 137.53 ±
14.32 mm/Hg in study group and 121.60 ± 8.09 mm/Hg in control group. The mean DBP was 87.73 ±
8.83 mm/Hg in study group and 71.03 ± 9.56 mm/Hg in control group. The results of the present study
indicate that the difference between the mean serum ferritin and mean SBP, mean DBP among the study
group and control group was found to be significant statistically (p=<0.005).
Conclusion: The current study found a positive association between the mean serum ferritin levels and
high blood pressure among the study participants