European Journal of Molecular & Clinical Medicine

Abstract

Typhoid fever is one of the most common bacterial diseases in Indian sub continent. Carriers are
found to be one of the cause of typhoid. A person may hold the typhoid germ asymptomatically
for days to years without showing any signs or symptoms of typhoid fever. The typhoid bacillus
continues to multiply in the gall bladder of such carriers. The bile duct transports it to the
intestine. The silent carriers are the source of typhoid germs that cause infections to recur1. With
over 21.6 million cases and at least 250,000 deaths per year, it remains a global public health
problem. Asia accounts for almost 80% of cases and deaths, with Africa and Latin America
accounting for the remainder. The disease has an incidence ranging from 102 to 2,219 per
100,000 of the population in developing countries like India2