Online ISSN: 2515-8260

Keywords : Lipoprotein

Study of Lipids and Lipoprotein Levels in uncomplicated Diabetes Mellitus Patients attending Shadan Hospital

Dr. Samatha Tulla; Dr. Siddique Ahmed Khan; Syeda Ayesha Siddiqua

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 7, Pages 1973-1978

Background: Lipid and lipoprotein levels are interrelated with diabetes mellitus. Abnormalities in the levels of total cholesterol (TC) or triglycerides (TAG) or low-density lipoprotein (LDL) cholesterol or very-low-density lipoprotein (VLDL) cholesterol or high-density lipoprotein (HDL) cholesterol or lipoprotein (a) [Lp (a)] is traditionally named as dyslipidemia. Diabetes mellitus has been known to be associated with lipid disorders and cardiovascular diseases. In patients with diabetes mellitus, dyslipidemia occurs earlier in life, leading to increased morbidity and mortality rates. The study aims to assess the changes in lipids and lipoprotein levels in uncomplicated diabetes mellitus patients.
Methods: A case-control type of study was conducted for 18 months (September 2011 to March 2013) at the Department of General Medicine, Shadan Hospital, Hyderabad. Ethical committee approval was taken before the study from the institutional ethical committee. A total of 120 subjects, 60 non-diabetic (healthy) control subjects with matching age and gender and, 60 cases of subjects with uncomplicated diabetes mellitus were enrolled based on predetermined inclusion and exclusion criteria.
Results: This study was conducted to evaluate the changes in lipids and lipoprotein levels between control (normal and healthy subjects) and case (subjects with uncomplicated diabetes mellitus) groups. The Mean±SD levels of total cholesterol, triglycerides, low-density lipoprotein cholesterol, very-low-density lipoprotein cholesterol, and lipoprotein (a) were higher in the cases group and showed statistical significance when compared with the control group.


Dr. Keshav Kumar Garg, Dr. Sankar Kalairajan, Dr. K. Praveen Gandhi, Dr. Sasmita Mishra

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 7, Pages 7208-7215

Background: Anemia is common disorder in India, although there are plenty of reasons attributable to anemia. There are studies reporting the beneficial effect of anemia on lipid profile. This research was conducted to study the pattern of lipid profile in anaemic patients.
Material & Method: Present hospital based cross sectional study was conducted among the patient more than 18yrs of age attending the OPD or admitted in medicine department Aarupadai Veedu Medical college & Hospital with diagnosed anemia. Study was done over a period of two years on patients with proven cases of anemia. After informed & written consent from the patients, detailed history, clinical assessment & laboratory investigation was done.
Result: In present study total of 280 patients fulfilling inclusion criteria are included in the study. The mean age of the patients was found to be 39.44±14.92yrs, among them 60% were female and 40% were male patient with female preponderance. There was significant positive strength of association of hemoglobin with the lipid profile which included the total cholesterol, LDL, HDL, triglycerides and VLDL cholesterol(p<0.05).
Conclusion: The present study showed a significant strength of association between the hemoglobin level and the lipid profile parameters. Also lower mean level of lipid parameters with severity of grade of anemia.

The Importance Of Uric Acid Level In Patients With Persistent Kidney Disease Of Predialysis Stages

Dano A. Egamberdieva; Botir T. Daminov; Iroda A. Ruzmetova

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 3, Pages 3417-3429

The study explores theory of relativity of acid levels with nephritic function, moreover as its role as a prognostic marker of cardio tube risk in chronic excretory organ diseases within the course of variable regression analysis, taking into consideration the adjustment of potential risk issues, the amount of uric acid was found to be a major factor influencing calculable capillary vessel filtration rate. The results of this study showed that elevated humor uric acid levels are related to the next risk of kidney malfunction.