European Journal of Molecular & Clinical Medicine

Sepsis is among the major reason of death in hospitalized patients. The hallmarks of sepsis are excessive inflammation, coagulation, and the suppression of fibrinolysis. It requires prompt diagnosis, immediate treatment with antibiotics & hemodynamic support. The early diagnosis of sepsis with immediate treatment can prevent its progression and decrease the mortality rate. The initial antibiotic to be given must be a broad-spectrum dependent over local sensitivity patterns. It should be daily assessed for de-escalation and cessation. The management is influenced more by appropriate treatments along with the antibiotics and fluid than by the specific intensive care.

Respiratory syncytial virus (RSV) is the most common respiratory pathogen in infants and young children. From the nasopharyngeal or conjunctival mucosa of infected individuals, RSV spreads to the lower respiratory tract causing acute bronchiolitis and pneumonia after an incubation period of 4 to 6 days. In addition to its well-documented tropism for the airway epithelium, it has been shown previously that RSV can also spread hematogenously and efficiently infect extrapulmonarytissues of human hosts. Furthermore, it has been shown in animal models that RSV can spread transplacentally from the respiratory tract of a pregnant mother to the lungs of the fetus. This report describes a documented case of neonatal RSV infection strongly suggestive of prenatal transmission of this infection in humans from an infected mother to her offspring.