Online ISSN: 2515-8260

Keywords : Azo compounds


Synthesis Of New Azo-Chalcone Compounds Derived From Imidazoline-4-one And Evaluation Of Their Biological Activity

1Ahmed N. Hameed; Abdul Jabar Kh; Haitham K R AL- Sharifi

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 3565-3589

compound (A) was synthesized by the reaction of BT
(benzoylthiourea) with ethyl chloroacetate and this represented the start point
for the synthesis of new azo compounds(1a-l) by using pyridine as solvent and
catalyst.Series of azo-chalcone compounds(3a-j) which contains a chalcons and
azo group in the same time were synthesized via exploitation the active
methylene group in compound (A). In this work all the chemicals were used to
the synthesis compounds obtained from various and deferent companies in a
high purity (Sigma-Aldrich,BDH,Fluka and ROMIL-SA), in addition to all
synthesized compounds have been characterized and identify by FT-IR,1HNMR
and GC-Mass and the melting point