European Journal of Molecular & Clinical Medicine

Background: Wound debridement is very crucial step for wound healing and prevention of infections complications. Traditionally, several types of wound debridement techniques have been used in clinical practice such as autolytic, enzymatic, biodebridement, mechanical, conservative sharp and surgical.
Aim & objective: Compared the surgical debridement and autolytic debridement methods for wound.
Results: This study involves selecting fifty patients suffering from acute or chronic wounds, randomly distributing them to the following groups irrespective of age, sex and etiology of wounds and then treating them with different methods of debridement as denoted by the group’s name Group I Surgical debridement group, Group II Autolytic debridement group. Male patients were predominant than female, mainly 41-60 years age groups. Discomfort reduction more in surgical group whereas pain and discharge reduction more in autolytic group.
Discussion: The choice of the debridement technique depends on type of ulcer/wound patient’s age, economic status, state of wound edges and skin, exudate and resources of the caregiver. Surgical debridement is low cost, highly sensitive and rapid acting but it can cause pain and invasive. Autolytic debridement is a painless, less invasive, less chance of infection and safe technique, but with slow action, so with high costs, because dressing are usually changed once a day.
Conclusion: Surgical debridement is the fastest way to remove the source of infection, promotes healing and helps accurate assessment of wound. Pain and discomfort are less in autolytic debridement.

Introduction: Umbilical hernias in adults are commonly acquired hernias. These are more common in women, and in conditions like pregnancy, ascites, obesity etc. More than 1 million hernia surgeries are done annually in India. Suture repair techniques have dominated ventral and incisional hernia repair over a century. The most popular of these techniques was the Mayo duplication. In larger hernias, suture repair requires the application of tension to the fascia in order to close the orifice.
Objectives of the study: To evaluate the outcome of onlay and pre-peritoneal open mesh repair in umbilical hernias in adults regarding operative time, ease of procedure, hospital stay, complications and recurrence if any.

Background:Chronic wounds result in significant functional impairment, reduction in
quality of life, and large financial costs for patients and the health care system. This
study intends to establish the efficacy of VAC in comparison with conventional
dressings in wound healing.
Materials & Methods: 65 wound patients of both genders were allocated to VAC and
conventional dressings, considering their diabetic and chronic conditions alternatively.
All patients underwent detailed clinical examination and relevant investigations and the
wounds were thoroughly debrided and the ulcer dimensions as well as the surface area
assessed.
Results: There were 32 patients in group I and 33 in group II. Maximum patients
(40.6%) in conventional dressing and (30.4%) in VAC dressing was seen in age group
51-60 years. Out of 65 patients 12 were females and 53 patients were males. Out of 12
females 8 underwent conventional dressings and 4 underwent vac dressings. Out of 53
male patient 24 underwent conventional dressings and 29 underwent VAC dressings.
There was no statistically significant difference in gender distribution in both methods
of dressings. Diabetic wounds were 25 each and chronic wounds were 3 in conventional
and 4 with VAC method. Accident induced traumatic wounds were 4 each in both
methods. The mean appearance of granulation tissue was 55.2% and 83.3%, wound
contractures in millimetre2 was 46.1 and 97.4 and duration of hospital stay was 16 and
8.76 in conventional and VAC group. The difference was significant (P< 0.05).
Conclusion: VAC dressing was superior to conventional dressing. As majority of our
patients were diabetic, VAC dressings facilitated early wound healing and decreased the
morbidity in our patients.

Primary goal in management of open fractures is prevention of infection of bone and soft tissue by early debridement, irrigation of wound and administration of broadspectrum antibiotics with stabilization of fractures. The pattern of organisms found in open fractures is important in the selection of antibiotics for prophylaxis and empirical treatment. In this prospective study, 50 consecutive patients of all ages, both the sexes, with open fracture of grade IIIB as per Gustilo- Anderson classification were evaluated for bacterial isolates. Higher rate of infection was found in patients with farm injuries and leg was most common site. The most common gram negative and gram positive bacteria isolated were E.coli and S.aureus respectively (19.5% each). On analysis of the predebridement, post-debridement, and third culture, positive pre-debridement culture showed maximum growth of Gram-positive bacteria. However, majority of these patients were found to have growth of different organism in their post-debridement culture reports.

Abstract: Introduction: These injure result from contact with faulty electrical wiring g or
high voltage power lines passing over the residences. Lighting is also an electrical injure the
extent of injuring is influenced by the duration of contact, current-voltage, type of current
(direct or alternate) the path of current and the resistance offered by tissues. Case
Presentation: A case of a 25-year-old male admitted in the burn unit on the date 22 October
2019 with complaints about he came in contact with the electric pole due to electrical shock
on 12/10/2019. He had wound over left hand up the wrist, wound over over the left axilla,
inner part of both thighs, head and back. The wound over the left hand was associated with
pus discharge, which was foul-smelling and scanty in amount, blood-stained.Interventions:
Generally, the burn victims with major burns are hospitalized and care is providing the burn
unit or ward. The goals during this phase are saving a life, maintaining and protecting the
airway, restoring hemodynamic stability and promoting healing and preventing or correcting
the complication. Outcomes: Over the short course of treatment, the patient significantly
improved in functional mobility, transfers, ambulation, and bed mobility. Progress even
further towards his goal of returning home. Discussion: The patient responded well to
treatment, however additional interventions could be utilized in the future to aid in greater
improvements