European Journal of Molecular & Clinical Medicine

Chemotherapeutic agents have long been used to treat cancer either as a single drug or as a
combination. Cancer drugs have a great potential to induce acute, chronic, reversible and
irreversible damage in any organ system. Ocular toxicity produced by chemotherapeutic
agents is relatively uncommon as eye is usually considered as a protected site. Many of the
side effects in the eye are usually undetected either by the patient or by the clinician.
However, some of these side effects which are potentially reversible and treatable in the early
stages, turn out to be irreversible by the time the symptoms are detected. Hence, it is
important for the ophthalmologist to be aware of the potential ophthalmic complications to
treat them or sometimes even to prevent them.
Ophthalmic complications of these chemotherapeutic agents are sometimes underestimated
and neglected. Priority is usually given to the life-threatening effects of the drugs. Ocular
surface side effects have been extensively examined by many authors, though the possible
underlying mechanisms are poorly understood [1][2].
The quality of life takes a huge hit when the patient develops side effects like continuous
watering or dry eye some of which can be easily managed before potential irreversible side
effects develop[3][4]. An ophthalmic baseline examination for all patients planned for multiple
chemotherapeutic cycles and those undergoing these cycles becomes indispensable part of
patient care.
The aim of our study was to compare the baseline ocular status of the patients undergoing
combination chemotherapy before the start of chemotherapy and after a minimum of three
chemotherapeutic cycles.

In this scientific article, determining the role of computer technology and
special effects in cinema as a new visual expression tool and, in this connection to the
filmmaking, the problems associated with film resolution, was analyzed. The purpose of
this article is to identify common features and regularities of the development of computerspecific
effects with the example of renowned films that have been created in this sphere.
This article also clarifies the role of special effects in the development of Uzbek cinema.
Achievements and imperfections in this field, as well as issues of artistic quality in
contemporary Uzbek cinema, and the importance of expanding and enriching the moral
world of the audience through visual aids, were also analyzed.

Pulmonary Tuberculosis (TB) is a disease caused by Mycobacterium tuberculosis. TB cases in Indonesia reached more than 300 per 100.000 populations meanwhile in Jakarta as many 24.775 cases, for East Jakarta as many 7.520 cases. Properly diagnose, and the granting of anti-tuberculosis drugs as well as monitoring of side effects are expected to reduce the number of TB incidence. The research aims to know the characteristic and side effects of anti-tuberculosis drugs against TB patients who were hospitalized in UKI Hospitalon January 2015 – September 2017. The method used is content analysis document that is retrospective with 212 populations. The research results obtained that most patients are male, age group 45 - 54, the level of education is senior high school, entrepreneurs, and has lived in Jatinegara. The most clinical manifestation of TB is cough and in the physical examination is vesicular sound with Ronchi (rales or crackles). The most work up of TB is x-ray and LED.Meanwhile, BTA examination only 40% with the most result is BTA positive. The most imaging of x-ray is infiltrating. The most prescribed is FDC. The distribution of adverse effect due to these drugs is the same (one each)