Online ISSN: 2515-8260

Keywords : Adenosine deaminase

Levels of adenosine deaminase and lactate dehydrogenase in the serum and CSF of TB meningitis patients

Dr. Zeenath Begum, Dr. Md Althaf, Dr. P Harsha Vardhan, Dr. P Mahesh Kumar .

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 7, Pages 9769-9783

Background: The high mortality rate of tuberculosis, along with the fact that it is one of the oldest human diseases, has made it a major focus of study for medical professionals in every corner of the globe. This bacterial infection, which is caused by the Mycobacterium tuberculosis complex, mostly affects the lungs but, in up to a third of patients, can spread to other regions of the body.
Methods: From December 2015 to May 2017, researchers from the Biochemistry department at MGM Hospital, a TB chest hospital in Warangal, did a case control study. The samples come from the TB and chest departments of MGM Hospital in Warangal and the general medicine department.
Results: The current research was carried out in MGM hospital in Warangal, India, specifically in the Biochemistry, General Medicine, and Tuberculosis and Chest Diseases Departments. Fifty participants with confirmed or strongly suspected tuberculous meningitis and fifty healthy controls were enrolled in the study. The levels of ADA, LDH, glucose, and protein were all reported in international units per liter.
Conclusion: Scientists and researchers in the fields of Tuberculosis and Chest Disease and General Medicine carried out the current study. The study included a total of 100 participants. There were 50 patients with confirmed or suspected TB meningitis and 50 controls.