European Journal of Molecular & Clinical Medicine

Aims and Objective: The aim of present study was to study and compare alterations in liver function tests and gamma glutamyl transferase in laparoscopic cholecystectomy.
Material and Method: It is a prospective study conducted in the department of General Surgery at Maharishi Markandeshwar Medical College and Hospital Kumarhatti, Solan from April 2021 to April 2022 and included 50 cases diagnosed with cholelithiasis. LFTs and GGT was done 24 hour before, 24 and 72 hours after the laparoscopic cholecystectomy. An informed and valid consent from the patients were taken to include in the present study. The data collected was analysed by students paired t-test.
Results: In this study we found laparoscopic cholecystectomy is the preferred treatment for cholelithiasis. However, due to pneumoperitoneum created during surgery can cause decrease blood flow to liver transiently, that leads to alteration of liver function tests. S. Bilirubin, SGOT, SGPT, GGT are deranged significantly after laparoscopy cholecystectomy but ALP is or not be raised significantly after 24 hours of surgery. These raised values decrease after 72 hours of surgery but not significantly. Mean age of our patients was 44.68 12.328 years. The incidence of cholelithiasis is more in females than males.