Keywords : Alpha-Blockers
Performance of alpha-blockers in distal ureteral calculus ejection
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 7, Pages 9538-9544
Background and objectives: Assessment of effectiveness of α blockers in eliminating distal ureteric calcification and determine Tamsulosin's and Alfuzosin's effectiveness in treating distal ureteric calculus.
Methods: A 120-patients Control Prospective Cohort research was conducted at Department Urology, Rajarajeswari Medical College and Hospital, Bengaluru, Karnataka, India. All individuals presenting a background of ureteric colic who showed up between August 2021 and July 2022 got considered for participation in the research.
Result: Group A patients were 27.0 (range 18 to 45) years old, Group B 26.8 (range 18 to 45), and Group C 25.4. (between range18 to 41 years). Most people were 21 to 30. All 3 groups had comparable age distributions. P = 0. 97, Men and women were equally represented in all 3 groups. Group A needed 3.8%, 16.67%, and 10% intervention in 6mm calculus, respectively. Group A, B, and C required intervention for > 6mm calculus at 96.1%, 83.3%, and 90%. All groups showed statistically significant differences. P =0.03, The placebo group averaged more than 6 analgesic doses.
Conclusion: Tamsulosin and Alfuzosin promote distal ureteric calculus evacuation. Tamsulosin and Alfuzosin had identical distal ureteric calculus ejection rates. Alpha-blockers lessen analgesics needs but not calculus ejection period