European Journal of Molecular & Clinical Medicine

Background: Necrotizing soft tissue infections (NSTIs) are a quickly deadly illness whose prognosis is dependent on early detection and treatment.
Methods: The study included 626 patients, 378 of whom were men and 248 of whom were women, ranging in age from 19 to 67 years. The research was carried out at Department of General Surgery, LSK Hospital, Kishanganj, Bihar for 5 years. The study's samples were taken from patients who came to the hospital with Necrotizing fasciitis. These individuals are undergoing clinical, radiological, and laboratory examinations. Tissue samples are taken for bacterial culture and sent to a laboratory for identification and antibiotic sensitivity testing. The area was examined using X-rays and CT scans. Blood samples were also obtained and sent to a laboratory for a full blood analysis.
Results: In compared to the control group, severe cases have the lowest mean value of WBC (7.1806±1.95788), the lowest mean value of haemoglobin (6.9260±2.25653), and the highest blood levels of creatinine (145.9758±2.33841), glucose (13.8547±1.71067), and the lowest serum sodium (94.0986±0.22220). At the 0.05 level, the mean difference is significant (P<0.05).
Conclusion: A necrotising soft tissue infection is a fatal disorder. It is critical to focus on the aetiology of such a problem in order to begin treatment as soon as possible in order to avoid mortality.