Online ISSN: 2515-8260

Keywords : COVID-19 infection



European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 6, Pages 332-337

Background: The immune system defends the host against many harmful microorganisms. The immune system has developed to contain various specialized cell types, signaling molecules, and functional responses to deal with this wide range of threats. In Covid-19 infections immune system is the key component for prevention of the disease. Hospital admission and duration of stay due to covid 19 infection have a considerable physical, financial, and psychological burden for the individual, family, and country. Diet has been shown to have a vital role in boosting one's immunity. Non vegetarian diet is traditionally considered to be immunity boosting as it is rich in protein, vitamins, and micronutrients.      
Aims and objective: To study the effect of dietary pattern on duration of hospital stay in patients with respiratory Covid illness
Material and Methods: This was a double blind retrospective cohort study comprising of 113 patients tested positive in RTPCR for SARS-CoV-2 and admitted at DCH located at super specialty hospital of Jayarogya Group of Hospitals, Gwalior, Madhya Pradesh, was studied retrospectively between July 2020 to October 2020. Patients were divided based on diet pattern into Group A (patients following a vegetarian diet; n=70) and Group B (patients following a non-vegetarian diet; n=43). The outcome was measured as the duration of hospital stay and comparison of diet type, age, and gender of patients. All these patients were discharge stable and case files of deaths were excluded. Non vegetarian diet was defined as inclusion of eggs, meet, fish in the routine diet whereas a vegetarian diet was exclusion of these items.   
Result: Out of 113 patients, most (61.94%) had a vegetarian diet, whereas 43 (38.06%) had a non-vegetarian diet. Duration of hospital stay was more in patients in Group A (10.71±5.5 days) than Group B (8.4± 4.7 days), p=0.0302. Hospital stay was longer (11.05 days) in older patients (>50 years) compared to younger patients (≤50 years) (9.2 days) (table 3).  In Group A, hospital stay was longer in those with age >50 years (11.4 days) compared to those with age ≤50 (9.2 days). On the contrary, older patients had shorter hospital lengths (9.9 days) than younger patients (10.09 days) in Group B (p value =     ).
Conclusion: A significantly shorter hospital stay was observed in patients of respiratory covid infection following a  non-vegetarian diet with Covid-19 infection.

Predictors of adverse clinical outcomes of recovered COVID-19 patients from a tertiary care hospital, Gujarat, India.

Tejas D Shah, Dipak B Solanki, Sudip V Bhavsar , Kinnari I Gupta, Dharmendra T Panchal, Tinkal C Patel, Vaidehi Gohil

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 6, Pages 768-777

SARS-CoV 2 virus infection present as varying degree of severity with many post viral complications.Although initial research was focused on the epidemiology, risk factors, clinical syndrome and treatment options; sufficient data is needed on sequelae of the patients who got discharged. The present study aimed to identify long term outcomes of COVID 19 recovered patients to safeguard their life in future.
Methods: The present longitudinal study included all 443 COVID 19 recovered patients who were admitted during the second wave at our tertiary care hospital from 1stApril to 25th May, 2021 and interviewed telephonically with series of questionnaire. Baseline demographic profile, comorbidities, clinical characteristics and investigatory findings were obtained from the hospital records and analysed for the long term symptoms and outcomes.
Results: Over a mean follow up period of 152 days, around 6% of the patients who recovered after acute COVID 19 infection died after the discharge. More than two third of patients were male. Diabetes and hypertension were most common comorbidities among the study population. Most common persistent symptoms was fatigue among the recovered population at follow up. Multivariate logistic regression analysis against the odds of post discharge mortality  revealed patients receiving advanced respiratory support  (AOR 5.2, 95% CI 1.8-15.1) and ICU stay during the hospitalisation (AOR 6.67, 95% CI 1.18-37.7) were predictors of post discharge mortality. 
Conclusion:  Fatigue was the most common symptoms observed after 5 months of discharge from acute COVID 19 infection. Overall post discharge mortality was 6% and admission in ICU and use of advanced respiratory support were associated mortality among recovered patients