Keywords : Chi-Square test
CORRELATION OF SEROLOGICAL MARKERS AND PLATELET COUNT IN DENGUE PATIENTS
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 4, Pages 1546-1553
Introduction: Dengue virus infection has emerged as a notable public health problem in recent decades . Laboratory evaluation of dengue Serological markers and platelet count help in early diagnosis and can be used as predictor to reduce the morbidity and mortality of dengue disease.
Aim: Aim of this study is to evaluate Dengue serological markers for early diagnosis of cases and to study the correlation between serological markers and platelet count in dengue positive cases .
Materials and Methods: This was a cross-sectional prospective study conducted in the Tertiary health care centre , Hyderabad.. All clinically suspected cases of dengue, reported to various outpatient departments, emergency services and admitted patients in the Hospital were included for this study, from July to September 2018 . The Chi-Square test and statistical software Epi info and MS excel was used to find out the statistical significance of the estimate.
Results: Among 700 blood samples were received from clinically suspected case of dengue , 125 (17.85%) cases were detected dengue positive out of which 65 (52%) cases showed platelet count less than 1 lakh. . In confirmed dengue cases, thrombocytopenia is more consistently found in dengue positive cases with only IgM and only NS1 positive cases compared to other serological groups.
Conclusion: Detection of dengue specific serological markers along with platelet count in the diagnosis of dengue, increases the early diagnosis so as to avoid complications significantly and can be used as prognostic marker to reduce the morbidity and moratlity of dengue disease.