Online ISSN: 2515-8260

Keywords : Clinical diagnosis activity index (CDAI)

Midterm analysis of the relationship between psoriasis skin severity and joint involvement

Dr Md Qamar Abdul Azeez, Dr M S Dilruba begum

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 4, Pages 526-535

Psoriasis is a common skin disease. Up to 30% of patients with psoriasis develop psoriatic
arthritis resulting, by far, the most prevalent coexisting condition. Aim :The purpose of this
study is to evaluate the prevalence of psoriatic arthritis amongst patients with psoriasis,to
describe the clinical patterns of arthritis in psoriasis and to evaluate the relationship between
skin severity and joint activity.
Methods :
This study is noninvasive , cross sectional study, carried out at Anil Neerukonda hospital,
NRI institute of medical sciences between January 2020 and January 2022 i.e for 2 years, in
which 400 patients presenting with psoriasis to the hospital were screened for psoriatic
arthritis according to CASPAR criteria,nail involvement were assessed by the Psoriasis Area
Severity Index (PASI). The Joint disease activity was measured by clinical diagnosis activity
index (CDAI).
Result :
In our study mean patient age was mean - 38.17 years, 216 patients (54%) were female and
184 male (46%) , 40 (10%) patients had Psoriatic arthritis out of which 16 (40%) had Family
History of psoriasis .The mean PASI of the patients with psoriatic arthritis was 3.105+3.04
and 8 out of 40 psoriatic arthritis patients (20%) had Nail changes. The clinical characteristics
of Psoriasis arthritis were most common pattern being Asymmetrical oligoarthritis 24
cases(60%), followed by Symmetrical polyarthritis 10 (25%), followed by
Spondyloarthropathy 5 (12.5%) and predominant Distal interphalangeal joint arthritis 3 (7.5
%) .The mean CDAI was 5.71+3.94 . There was no significant correlation of clinical
diagnosis activity index (CDAI) with PASI.
There is a relatively low prevalence of joint manifestations among patients with psoriasis
presenting to our hospital. There was no significant correlation between the severity of skin
involvement(PASI) and joint manifestation or arthritis(CDAI).