Online ISSN: 2515-8260

Keywords : borderline

A Prospective hospital based observational assessment of patient with ovarian malignancies

Dr. Deepak Thakker, Dr. Shailendra V Mangnale

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 2, Pages 2127-2133

Aim: To analyze the clinical presentation and histopathological types of ovarian malignancies.
Material and methods: A Prospective hospital based observational study was conducted in the Department of Obstetrics and Gynaecology at VIMS, Dahanu for the period of 1.5 years. Total 100 cases of ovarian tumours were included in this study. The tumours were cut and allowed to fix in 10% formalin for 24-48 hours. After formalin fixation, multiple bits were taken for histopathological examination. The blocks were cut at 3-5 microns thickness and stained with Haematoxylin and Eosin. Detailed microscopic examination of the tumour was done.
Results: Out of 100 cases of ovarian tumours, 71 were benign, 6 were tumours of low malignant potential and 23 were malignant. The youngest patient was 12 months and the oldest was 67 years forming a range of 18 months to 67 years. Highest incidence of ovarian tumour was noted in the 40-50years 38cases out of 100 cases accounting for 38%. Highest incidence of benign ovarian tumour was noted in 30-40 years 26 cases out of 71 accounting for 36.62%. Highest incidence of malignant tumour was noted in the 40-50years 12 out of 23 cases accounting for 52.17%. 37% of the patients complained of dull aching lower abdominal pain, 24% complained of abdominal mass and 6% of the patients gave history of menstrual disturbance like menorrhagia. Urinary disturbances were found in 5% patients with tumours. Out of 100 patients 9 patients were not married and all were below twenty years of age. Among married, 83were parous and remaining were 8 nulliparous. Out of 100 cases of ovarian tumors, 29 were associated with appendicitis and 14 were associated with uterovaginal prolapse.
Conclusion: The ovarian tumors manifest a complex and varied spectrum of clinical, morphological and pathological features. Correlating the clinical parameters and categorizing the tumors according to the WHO classification help us in coming to an early diagnosis, management and hence in the prognosis of ovarian tumors.

Hypertension with reference to Left Ventricular Hypertrophy with Reference to Left Ventricular Mass Index

Dr. Amit R. Porwal, Dr. Anil Bhattad, Nitin B. Jadav

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 2, Pages 2955-2974

Better understanding and early recognition of hypertrophy in hypertensive patient helps with effective treatment and prevention of cardiovascular events and morbidity.
It has been established that anti-hypertensive therapy may diminish LVH and hence lessen the risk of serious cardiovascular events in individuals with hypertension. Left ventricular hypertrophy (LVH) is an adaptation of the heart, specifically the left ventricle, to increasing ventricular stress.
Subjects with borderline isolated systolic hypertension in the Framingham Heart study also had modestly elevated left ventricular (LV) layer thickness.1 It's widely recognized that left ventricular hypertrophy is linked to high blood pressure and the cardiovascular complications that come with it..