European Journal of Molecular & Clinical Medicine

Purpose: Corneal ulcer is one of the important ophthalmic condition causing significant morbidity especially in the developing countries. Bacteria and fungi are frequently responsible for suppurative corneal ulcers especially in the developing countries. The present study aimed to know the safety and efficacy of topical and intrastromal injection of Amphotericin B in the management of non-responding fungal corneal ulcer patients.
Methodology: It was a hospital based prospective, non-randomized, analytical study. Thirty patients of non-responding fungal corneal ulcer of any age group, of either sex were studied. Cases were studied in terms of clinical examinations, relevant investigations, appropriate treatment and documentation.