Keywords : QTc prolongation
Study of association of ECG changes to the site of bleed (sob) in nontraumatic spontaneous intracerebral hemorrhage (ICH) patients
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 2, Pages 1187-1192
Background: The annual incidence of intra cerebral hemorrhage (ICH) is 25 cases per 1, 00,000/year. Although ECG abnormalities are well known in ischemic stroke and subarachnoid hemorrhage these change have been rarely been investigated systematically in patients with ICH. Present study was aimed to study any association between ECG changes to the Site of Bleed (SOB) in non-traumatic spontaneous intracerebral hemorrhage (ICH). Material and Methods: Present study was a prospective, observational study, conducted in patients confirmed of ICH on CT scan. Each case was examined in detail with history, clinical features, ECG readings & CT scan findings.
Results: In present study, male to female ratio was 1.7:1. Maximum number of patients were from > 60 years age (52%). The various CT scan findings noted in the study were < 50 cc volume of hematoma (52%), presence of mass effect (40%) & presence of intra ventricular communication (38%). The most common site of bleeding was putamen (40%) followed by thalamus (30%), lobar (14%), brainstem (10%) & cerebellum (6%). The most common ECG findings in our study were Left Ventricular hypertrophy (56%) followed by prolonged QTc (54%), T wave inversion (56%), Left axis deviation (46%), Tachycardia (36%), ST-T changes (28%), Q waves (22%), Tall T wave (8%), VPC (8%) and RBBB changes (8%). In present study, there was statistically significant association was noted between LAD, IVC and LVH with ECG changes (p<0.05).
Conclusion: Significant association could not be established between specific site of bleed and ECG changes even though the proportions ECG changes to Site of bleed was significant.