Keywords : Core needle biopsy
Diagnostic Accuracy of Ultrasound Guided Core Needle Biopsy in Various Breast Lesions
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 3, Pages 2225-2231
Background: Breast cancer is the most common female cancer worldwide representing nearly a quarter (25%) of all cancers. Diagnosis of breast cancer is carried out by three medical members, the surgeon, who covers breast examination, the radiologist for mammography and ultrasound, and the pathologist for fine-needle aspiration cytology (FNAC) and core needle biopsy (CNB). Aim of present study is to assess the accuracy of ultrasound guided core needle biopsy in various breast lesions
Material & Methods: A hospital based prospective study done on 100 cases of various breast lesions reporting to the Surgery Department, J.L.N. Medical College and Associated Group of Hospitals, Ajmer, Rajasthanwithin study duration and eligible as per inclusion criteria were included in the study from January 2020 to December 2021. Then an ultrasound guided biopsy specimen is obtained by means of four successive insertions with different angulations of the needle into the core of the lesion. The quantity and quality of the material obtained is judged after immediate immersion of the specimen in fixative, and then specimen is sent to histopathology department. And the core needle biopsy report is compared with the excision biopsy report of the breast lump.
Results: Our results showed that the mean age was 38.79 ± 13.98 yrs (age range 18-75 yrs). On USG guided core needle biopsy and excision biopsy, 53% were found benign tumor, and 47% were carcinoma. Sensitivity is 100% and specificity is 100%. There was no false positive and false negative case present in this study.
Conclusion: We concluded that Ultrasound guided Core needle biopsy can be reliably used for preoperative diagnosis of breast lumps as the first diagnostic step with high sensitivity, specificity, and accuracy for both malignant and benign lesions. However, benign lesions, diagnosed this way, must be followed by frequent examinations.