Online ISSN: 2515-8260

Keywords : Alcohol liver disease

Profile of alcoholic liver disease in eastern Indian population – A prospective study

Md Israrul Haque, Kumar Abhishek, B P Singh

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 265-273

Introduction: Alcoholic liver disease (ALD) is a life-threatening disorder which has deadly
consequences over uncontrolled alcohol consumption. Excessive alcohol ingestion is the
forefront cause of death in people aged 15-49 years. Alcohol is the most common cause of
liver cirrhosis in many countries in the world.1 Alcohol induced toxicity is the 3rd cause of
morbidity. The liver is the largest and the most complex organ in the body since it runs
multiple functions in the body which includes secretion of proteins and enzymes, purification
of toxins, anabolic and catabolic functions and regulation of cholesterol. It is primarily
involved in the metabolism of alcohol and hence it is the most susceptible organ that
undergoes alcohol related injuries. Alcohol acts as a behavioural stimulant at lower blood
levels but at its higher level it acts as a central nervous system depressant damaging the
cerebellum badly which alters the gait of a person.