European Journal of Molecular & Clinical Medicine

BACKGROUND-Various comorbidities may show positive association with CLBP including respiratory disorder, cardiovascular disease, diabetes mellitus, anemia, obesity and mental health conditions. AIMS &OBJECTIVES-1.To study the clinical and aetiological profile in patients with chronic low backache 2.To study the association of various comorbidities with chronic low backache with special reference to axial spondyloarthritis. MATERIALS AND METHODS-Present study was a prospective one. All cases with chronic low backache  >18 years were included as subjects. Those excluded were patients with acute lower backache, age < 18 years, lower backache due to trauma, congenital causes of lower backache, those with a history of spinal surgery and bed ridden patients. Disease activity of Axial Spondylitis was determined using Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Ankylosing Spondylitis Disease Activity Score (ASDAS) and the functional assessment was done using Bath Ankylosing Spondylitis Functional Index (BASFI). In addition to X-ray L-S spine, MRI L-S spine was done in all patients.  Statistical analysis was done by SPSS software, version 19.RESULTS-Mean age of participants in this study was 46.89 years. Male to Female ratio was 2:3.Comorbidities were Hypertension in 25 (25%) Diabetes 11 (11%) COPD 9 (9%), dyslipidaemia 12 (12% hypothyroidism 3(3%), anemia 3 (3%), Coronary artery disease in 7(7%), Cerebrovascular Accident (CVA) 2 (2%), anxiety 4 (4%) and depression 2 (2%). 11 (11%) had axial spondyloarthritis, 5 (5%) osteoarthritis and 1 (1%) had rheumatoid arthritis. Axial Spondyloarthritis was significantly higher in males( P- value 0.025) and in age group less than 40 (<40 years) (P- value 0.002).There was significant association of anemia with axial spondyloarthritides(P-value 0.031). In patients with axialspondyloarthritis  was significant association of BASDAI(P- value-0.003),BASFI (P-value 0.001) and ASDAS( P -Value 0.009)with comorbidities. CONCLUSION- On the basis of our study we conclude that lower back pain is a multifactorial phenomenon.

Vitamin D has a significant role to play in bone metabolism and neuromuscular function. Several researchers have indicated that Vitamin D deficiency may be possibly related to musculoskeletal pain including chronic low back pain.
Aim: We aimed to examine the relationship between the levels of vitamin D and patients with chronic low back pain and to investigate its effects on pain and functional capacity.
Materials and Methods: Two hundred and sixty patients (Female/Male:110/150) with complains of low back pain for more than three months, aged between 18 to 60 years and both genders, participated in the study. Visual Analog Pain Scale (VAS) was used to measure the state of pain. Pain-related functional capacity was evaluated using Modified Oswestry Disability Questionnaire (MODQ). Patients were classified into three groups based on their serum vitamin D levels: Sufficient ( 30 ng/mL), insufficient (20.1-29.9 ng/mL) and deficient ( 20 ng/mL).

Background: The present study was conducted for assessing prevalence of chronic low
back pain among daily wages workers.
Materials & methods: A total of 200 daily wages workers were enrolled. Complete
demographic details of all the patients were obtained. A questionnaire was prepared for
assessing the prevalence of chronic low back pain. The Oswestry Disability Index (ODI)
was assessed in all the patients with chronic low pain. Patients with history of systemic
illness or any known drug allergy were excluded. All the results were recorded in
Microsoft excel sheet and were analysed by SPSS software.
Results: Out of 200 daily wages worker, chronic low back pain was seen in 82.5 percent
of the patients. Mean duration of symptoms was 7 to 9 months seen in 46 subjects while
it was between 10 to 12 months in 44 subjects.
Conclusion: Daily wages workers are significantly affected by chronic low back pain