Online ISSN: 2515-8260

Keywords : Diabetic

Study to Assess the Efficacy of Collagen Dressing in Diabetic Foot Ulcer Patients

Sadhna Tiwari, Sana Tiwari

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 10929-10935

Introduction: Diabetic foot has become the common indication for hospital admissions
among diabetics. The diabetic foot commonly begins as an ulcer. So rapid and extensive
is the underlying damage that approximately 20% of these patients end up with
amputation. The present study has been performed to compare the efficacy of collagen
dressing with that of conventional dressing materials like silver sulfadiazine,
nadifloxacin, povidone iodine.
Materials and Methods: Fifty patients (40 males and 10 females) were procured to be
included to experimental group who were treated using collagen dressing and they form
the study group. Control treatment was performed on 25 patients (21 males and 4
females) at the same period. All the quantitative values were noted as mean± standard
Results: 1. The final ulcer sizes (by the 3-week measurement) ranged between 0.2 and
4.2 cm2 (mean, 1.11 ± 1.19 cm2) in the experimental group, and ranged between 0.1 and
12.8 cm2 (mean, 2.52 ± 2.61 cm2) in the control group. It was found that all of 25
patients of the experimental group were reported with shrinkage of wound area and
depth over 30% at the third week regardless of wound location, duration, and grade. In
contrast, the improvement of only 5 ulcers in area over 30% at the third week was
observed, and 6 in depth.
Conclusion: Collagen dressing also might also provide supplementary advantages of
patients’ comfort and compliance as well as maintenance of ideal healing environment.
In order to confirm the usefulness and wound healing potential of collagen dressing in
the management of diabetic foot ulcers, future research with longer follow-up periods
should be conducted.

Assessment of lipid profiles of young diabetic and nondiabetic stroke patients: A teaching hospital based study

Dr. Gautam Gupta

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 1, Pages 986-992

Background:Lipid profile in patients with cerebrovascular disease and to determine
significant correlation between them. To ascertain the effect of age and sex on serum lipid
profile.The diagnosis of diabetes in a stroke patient would change the initial management of
that patient, specifically with respect to other risk factors like lipid and blood pressure
Aims and Objectives: To study lipid profile in diabetic and non-diabetic newly diagnosed
young stroke patients.
Materials and Methods: A total of 138 patients were admitted during study period were
selected by simple random sampling with acute stroke in the study. Fasting total cholesterol,
triglycerides, high density lipoprotein cholesterol (HDL-C) and low density lipoprotein
cholesterol (LDL-C) were measured from venous blood samples.
Results and Observations: The mean HbA1c for group D and group ND were 9.04±1.02
and 4.85±0.45 respectively. This difference in HbA1c among patients in two groups was
statistically significant. The mean values of LDL, VLDL, total cholesterol and triglycerides
showed significant association between two groups. Levels of HDL were significantly lower
in Group D as compared to Group ND.
Conclusion: The lipid profile of LDL, VLDL, total cholesterol and triglycerides showed
significant higher range in diabetic patients as compared to non-diabetics while HDL was
lower in diabetic patients as compared to non-diabetics.


Raghad Jameel Alhajaji, Atef Mohammad Raffa, Turki Abdulqader Dawaji, Asmah Ali Miswak, Haneen Mohammad Alshanqity, Abdulrahman Ahmad Alshamrani Wael Abdulqader Gamloo, Juman Maid Albajaly, Fahad Abdulmukrem Alsulami, Raeed Mustafa Rommani

European Journal of Molecular & Clinical Medicine, 2019, Volume 6, Issue 1, Pages 394-405

      Influenza is a seasonal epidemic with main symptoms that include fever, cough and muscle aches. Fever is a big distinguishing component between a cold and influenza. Some other common symptoms which may or may not be seen with a cold as well are headache, chills, loss of appetite, fatigue and sore throat. diabetes, influenza is a significant burden on the healthcare systems. A significant issue and a significant big health concern happen every year is looking how we could mitigate and manage it and obviously take the burden off the health care system. Diabetic patients, as other chronic diseases patients, could catch the influenza infection, which is a respiratory infection caused primarily by influenza A and Influenza B. Diabetes Mellitus (DM) is a major health problem worldwide. It is a number of metabolic disturbances that is characterized and identified by the presence of hyperglycemia in the absence of treatment.
Aim of the study: to assessment of the Prevalence of Influenza Immunization among Diabetic Patients attending Primary Health Care Center In Makkah Al-Mokarramah,2019.
 Methods: A Cross-sectional analytical study was carried out in the city of Makkah among diabetic patients attending  Primary Health Care Center during  the October to December 2019, the Sample size patients participants.  Our total participants were (300).
Results: shows the majority of participant (39.5%) have average level of total attitude of diabetic patients towards seasonal influenza vaccination followed by (29.5%) of participant weak while Range(7-19) and Mean ±SD(13.065±3.822), X211.59 P=0.003.Conclusion: Undermining the effect of influenza and misconceptions on the effectiveness of the vaccine could much be improved by increasing awareness and knowledge, seasonal vaccination among diabetics in KSA is low. Level of knowledge and perception are the main barriers to vaccination. Health care provider’s advice may be an important key predictor of previous influenza vaccination and they should continue to educate and encourage all diabetics to get vaccinated for influenza at least once yearly.

Assessment Of The Knowledge Diabetic Retinopathy Among Patients With Type 2 Diabetes At Makkah, Saudi Arabia 2019. Cross-Sectional Study

Adel Saeed Ali Alzahrani, Nawaf Suhaim Al-Atiani

European Journal of Molecular & Clinical Medicine, 2019, Volume 6, Issue 1, Pages 543-556

1. Background
Diabetic retinopathy (DR) is a well-known complication of diabetes mellitus (DM) and a major cause of
vision loss. Increased knowledge of DR is crucial for the prevention and early diagnosis of the disease and
preservation of vision, diabetes mellitus is a disorder, characterized by an imbalance in blood glucose
levels. The prevalence of diabetes mellitus is increasing globally.The global diabetes prevalence in 2019 is
estimated to be 9.3% (463 million people), rising to 10.2% (578 million) by 2030 and 10.9% (700 million)
by 2045. Long term, continuous hyperglycemia leads to vasculature-related disorders, including those
affecting the eyes, such as retinopathy, diabetes mellitus is an endocrine disease with chronic elevation in
blood glucose levels. If not managed, it can lead to multi-organ damage also diabetes mellitus is a
metabolic disease that is characterized by distortion in the metabolism of carbohydrates, lipids, and
proteins and involves hyperglycemia. Diabetes mellitus has different types. Several complications are
associated with diabetes including diabetic retinopathy.
This study aimed: This study aims to assess the knowledge of diabetic retinopathy and compliance with
diabetic retinopathy patients in Makkah, Saudi Arabia.
Methods: cross-sectional study was conducted among the diabetic population from May to September 2019
in Makkah, Saudi Arabia. The patients were selected randomly from the general population visiting the
Makkah diabetic center and primary healthcare clinics in Makkah. A self-administered questionnaire was
distributed to assess the knowledge of diabetes and its complication diabetic retinopathy. Our total
participants were (300)
Results: Conclusion: The level of knowledge regarding diabetic retinopathy among participants with
diabetes type 2 in Makkah is relatively high. However, participants’ motivation to attend an ophthalmology
clinic for an eye assessment was poor in the study, thus delay early diagnosis and management.