Online ISSN: 2515-8260

Keywords : signs

Comparative study to evaluate the efficacy of oral azithromycin and oral doxycycline in refractory meibomian gland dysfunction

Dr. Kainat Chaudhary, Dr. Charu Jain, Dr. V.K. Malik

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 407-414

Aim: To assess the efficacy and safety profile or oral azithromycin with oral doxycycline
in patients with refractory meibomian gland dysfunction.
Material and method: This prospective randomized control study comprised of 60
patients attending the outpatient Department of Ophthalmology at Subharti Medical
College. All cases underwent a detailed evaluation including visual acquity, anterior
segment slit lamp examination of lid margins, tear minuscus, conjunctiva, cornea and
tear film. Patients aged 18-70 were included in the study and the age matched
randomization was done in two groups i.e. Group A (Oral Azithromycin 500mg on day
1 and then 250mg per day for next 4 days) and Group B (Doxycycline 100mg twice a
day for 7 days and then 100mg once a day for next 21 days). All patients underwent
complete ophthalmic examination and the signs and symptom scores were recorded
prior to the treatment subsequently at 1 month, 3 months and 6 months post treatment.
Results: At last follow-up, there was distinct improvement in all the symptoms and
mean score of all the signs in both the groups. The decrease in mean score was more in
group A as compared to group B, however statistically significant was found in bulbar
conjunctival redness, meibomian gland plugging, eyelid margin redness and ocular
surface staining. Side effects were more in Doxycycline group as compared to
Azithromycin group.

A hospital based observational assessment of the distribution of different temporomandibular joint disorders in complete dentures patients

Dr. Shashank Katiyar, Dr. Nilesh Pagaria, Dr. Partho Shankar Chakraborty, Dr. Deeplaxmi Dewangan, Dr. Ashish Dewangan

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 1288-1292

Aim: To determine the prevalence of temporomandibular disorders (TMD) in patients wearing complete dentures (CD).
Material and Methods: This study was carried at the department of dentistry for a period of 1 year. 100 completely edentulous patients in the age group of 22-74 years who did not complain of any TMD and were denture bearers with a varied denture wearing span, were examined for TMD signs and symptoms included in the study.
Results: Out of a total of 100 subject sex amines, the majority of the patients is 28% fell in the age group of 50-60 years, followed by 40-50 years 22%. There was no statistically significant association between different genders and age (P [χ2=1.722, P (χ2>1.722) = 0.9885. In the distribution of patients with or without TMD, 61.67% of males out of the total male subjects and 65% of females out of total female subjects showed the presence of signs. The difference was found to be statistically insignificant (P [χ2=0.347, P (χ2>0.365) = 0.5476). 42% of the subjects had 1-3 years of edentulous span followed by32%withmorethan 5 years of edentulous span and 26% of the subjects showed 3-5 years of edentulous span. 34% of the subjects showed limited mouth opening assign of TMD followed by jaw deviation which is shown by 27 (27%) of the subjects.
Conclusion: With an increase in the number of patients wearing CD, it becomes mandatory for dentists to be aware of the consequences of denture use over the anatomy and physiology of TMJ to provide quality prosthodontics treatment. The most common finding was limited mouth opening while crepitus and clicking were the least encountered


Abdullah Ahmad Alzahrani, Abid Ahmad Masi AlMalki, Marwan Lafy Aljabri, Mamdouh Lafi Aljabri, Yehya Ahmed Almalki, Hassan Owysh Alsolami, Mohammad Lafy Aljabri, Suliman khairat Al Ansari

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 9, Pages 3979-3991

     Overcoming the scourge of malaria infection is possible when healthcare workers have good levels of understanding and attitudes towards the disease, which will influence their treatment practices. Saudi Arabia and Yemen are the only two countries in the Arabian Peninsula that are yet to achieve malaria elimination. This study assessed Knowledge of Malaria fever causes and symptoms among health care workers at the primary healthcare in Makkah City at Saudi Arabia. Malaria is one of the deadliest mosquito-borne diseases in the world. More than 80% of the total populations are at risk of malaria in the 22 countries in Asia and the Pacific. South Asia alone is home to an estimated 1.4 billion people at risk of contracting malaria.
 Aim of the study: The study aimed to assess the knowledge about Malaria fever causes, signs and symptoms among health care workers at the primary healthcare in Makkah City at Saudi Arabia.
Methods: Across sectional descriptive study conducted among including health care workers at the primary healthcare in Makkah Al-Mokarramah city, during the October to December, 2020, the Sample size of medical practitioners. Our total participants were (350).
Results: shows the
Total knowledge of the malaria fever results show the majority of participant had weak information were(62.6%) while average of the Knowledge about participants  signs of the malaria fever were(33.4%) the data ranged from(1-24) by mean ±SD(11.094±4.503) and a statistical significant relation While Chi-square X2 180.109  and P=value 0.001and  that is a significant positive correlation between Knowledge about causes and signs were r= 0.70) and p-value =0.001
 Conclusion: Malaria remains a public health problem in most governorates of KSA region. Health professionals have suboptimal knowledge and practice levels regarding causes, signs, symptoms, standard precautions of infection control, while most of them have positive attitude. The identification and monitoring of malaria transmission hotspots and predictors would enable control efforts to be intensified and focused on specific areas and therefore expedite the elimination of residual malaria from the whole region
 Therefore, it is recommended to enforce their training

A clinical Study of inguinoscrotal swelling in children

Dr. Rashmi Vidya Dsouza, Dr. Uchil Sonali Raghav, Dr. Avinash Jagannath

European Journal of Molecular & Clinical Medicine, 2018, Volume 5, Issue 1, Pages 576-588

The characteristic bulge in the groin which disappears at times and then recurs may not be present at the time of examination, however, and the surgeon may be compelled to rely on the description given by a competent observer. The most important aspect of the management of neonatal inguinoscrotal swellings relate to its risk of incarceration, strangulation which include gangrene of bowel, testis and ovaries. A prompt early and appropriate treatment is necessary to avoid various complications.