Online ISSN: 2515-8260

Keywords : signs

Comparative study to evaluate the efficacy of oral azithromycin and oral doxycycline in refractory meibomian gland dysfunction

Dr. Kainat Chaudhary, Dr. Charu Jain, Dr. V.K. Malik

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 407-414

Aim: To assess the efficacy and safety profile or oral azithromycin with oral doxycycline
in patients with refractory meibomian gland dysfunction.
Material and method: This prospective randomized control study comprised of 60
patients attending the outpatient Department of Ophthalmology at Subharti Medical
College. All cases underwent a detailed evaluation including visual acquity, anterior
segment slit lamp examination of lid margins, tear minuscus, conjunctiva, cornea and
tear film. Patients aged 18-70 were included in the study and the age matched
randomization was done in two groups i.e. Group A (Oral Azithromycin 500mg on day
1 and then 250mg per day for next 4 days) and Group B (Doxycycline 100mg twice a
day for 7 days and then 100mg once a day for next 21 days). All patients underwent
complete ophthalmic examination and the signs and symptom scores were recorded
prior to the treatment subsequently at 1 month, 3 months and 6 months post treatment.
Results: At last follow-up, there was distinct improvement in all the symptoms and
mean score of all the signs in both the groups. The decrease in mean score was more in
group A as compared to group B, however statistically significant was found in bulbar
conjunctival redness, meibomian gland plugging, eyelid margin redness and ocular
surface staining. Side effects were more in Doxycycline group as compared to
Azithromycin group.


Abdullah Ahmad Alzahrani, Abid Ahmad Masi AlMalki, Marwan Lafy Aljabri, Mamdouh Lafi Aljabri, Yehya Ahmed Almalki, Hassan Owysh Alsolami, Mohammad Lafy Aljabri, Suliman khairat Al Ansari

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 9, Pages 3979-3991

     Overcoming the scourge of malaria infection is possible when healthcare workers have good levels of understanding and attitudes towards the disease, which will influence their treatment practices. Saudi Arabia and Yemen are the only two countries in the Arabian Peninsula that are yet to achieve malaria elimination. This study assessed Knowledge of Malaria fever causes and symptoms among health care workers at the primary healthcare in Makkah City at Saudi Arabia. Malaria is one of the deadliest mosquito-borne diseases in the world. More than 80% of the total populations are at risk of malaria in the 22 countries in Asia and the Pacific. South Asia alone is home to an estimated 1.4 billion people at risk of contracting malaria.
 Aim of the study: The study aimed to assess the knowledge about Malaria fever causes, signs and symptoms among health care workers at the primary healthcare in Makkah City at Saudi Arabia.
Methods: Across sectional descriptive study conducted among including health care workers at the primary healthcare in Makkah Al-Mokarramah city, during the October to December, 2020, the Sample size of medical practitioners. Our total participants were (350).
Results: shows the
Total knowledge of the malaria fever results show the majority of participant had weak information were(62.6%) while average of the Knowledge about participants  signs of the malaria fever were(33.4%) the data ranged from(1-24) by mean ±SD(11.094±4.503) and a statistical significant relation While Chi-square X2 180.109  and P=value 0.001and  that is a significant positive correlation between Knowledge about causes and signs were r= 0.70) and p-value =0.001
 Conclusion: Malaria remains a public health problem in most governorates of KSA region. Health professionals have suboptimal knowledge and practice levels regarding causes, signs, symptoms, standard precautions of infection control, while most of them have positive attitude. The identification and monitoring of malaria transmission hotspots and predictors would enable control efforts to be intensified and focused on specific areas and therefore expedite the elimination of residual malaria from the whole region
 Therefore, it is recommended to enforce their training