Online ISSN: 2515-8260

Keywords : MDR-TB

A study on clinical presentation of MDR-TB and Its treatment pattern

Dr.Raghu BP, Dr.Raghavendra MK,Dr.Aravindh Ram VR,Dr.Yunus Sheriff, Dr.Deepak UG

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 1, Pages 473-477

There are several reports that many co morbidities can both accelerate TB disease and complicate TB treatment. It is therefore important to identify these co morbidities in people diagnosed with TB in order to ensure early diagnosis and improve co-management. When these conditions are highly prevalent in the general populations they can be important contributors to the TB burden. The research students attended ward rounds on a daily basis and collected the cases which are mentioned under the inclusion criteria. All the required parameters were analyzed thoroughly and data was pooled and analyzed. Identified adverse drug reactions and drug interactions were reported to the consultant physician on time and on daily basis. Among 250 patients, majority 182(72.8%) of the patients were found to be without any comorbidities & 68(27.2%) were with co morbidities. Patients with co morbidities were 68, out of which male patients 62(91.2%) were more in number compared to female patients 6(8.82%). There were 55 (80.88%) DM patients followed by COPD-7 (10.29%) and HIV-6 (8.83%).


European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 4, Pages 1560-1564

Background: Tuberculosis (TB) is a chronic, progressive mycobacterium infection, often with a period of latency following initial infection. The first line and second line of TB treatment show some of the side effects on the individual. Past studies had shown that second line MDR-TB treatment causes an effect in the auditory domain, but there is a shortage of studies related to drugs used in MDR-TB on speech perception in noise.
Objectives: The study aimed to assess the speech perception in noise in individuals with and without tuberculosis.
Material and method: A total of 80 participants in the age rane of 20 to 40 years were included in the study. Further, these participants were categorized into two groups. The first group having individuals without tuberculosis while the second group included individuals with tuberculosis. All the participants were initially undergone for basic audiological evaluation followed by Quick Sin test in Kannada.
Results and discussion: The results showed that there was a significant difference between the groups on speech perception in noise test.
Conclusion: It can be concluded from the current study that individuals with tuberculosis showed poorer performance compared to individuals without tuberculosis on speech perception in noise test.