European Journal of Molecular & Clinical Medicine

 Background: About two-thirds of the benign intraspinal neoplasms are intradural extramedullary spinal cord tumours (IESCT). On rare occasions, they exhibit neurological involvement ranging from acute to chronic, necessitating urgent surgical intervention.
Methods: Here, we examined a group of 10 intradural extramedullary tumours treated between 2020 and 2022 by a single orthopaedic surgeon at Rajshree Medical and Research Institute, Bareilly's department of orthopaedics. Patients were followed up forat least two years. Clinical and functional outcome of these patients were evaluated by Karnofsky Performance Score [KPS], and Modified McCormick scale.
Results: Thoracic spine 07 (70%) and junctional tumours 3 (30%) were the major sites of the majority of IESCT tumour in our study.
There were 5 meningiomas, 2 schwannomas, 2 inflammatory, and 1 benign cyst on histo-pathological analysis. Meningiomas were typically found dorsal spine and dorso-lumbar junction, while schwannomas were found in the middle of the dorsal region.
Both KPS and the Modified McCormick scale were significantly improved after surgery.
Conclusion: MRI scan with constrast can easily identify the majority of benign intradural extramedullary tumours. It was observed that earlier diagnosis of neurological involvement were associated with good prognosis. Notably, surgical intervention is followed by positive functional outcomes.

Background: Chronic otitis media is an important cause of morbidity affecting all ages leading to variety of complications which has major impact on the patients and more so in Covid pandemic. Study to see the change in findings of culture and sensitivity data in chronic Otitis media during Covid pandemic and hence modify the treatment plan.
Aims: To study the bacteriology associated with the chronic otitis media and study any change in findings of bacteriology of chronic otitis media during COVID pandemic.
Subjects and methods: The retrospective study was done. The culture and sensitivity data during Covid pandemic was collected from Jan 2020 to Jan 2021 from ENT centre and their analysis and interpretation done according to age, types of culture and their sensitivity.
Result: In the total 100 cases of culture and sensitivity results during pandemic, pseudomonas aeruginosa was the most common organism isolated and showed highest sensitivity towards piperacillin/tazobactam and polymyxin B. Staphylococcus aureus was second most common which showed highest sensitivity towards linezolid and teicoplanin. Both showed lowest sensitivity towards ciprofloxacin. There was no change found in the bacteriology culture during the Covid pandemic which was compared from available literature.
Conclusion: the change in the findings of culture and study of chronic otitis media based on the study done shows almost no difference with the pre-pandemic times. But high antibiotic resistance implicates the careful use of antibiotics in treatment and avoiding empirical method of treatment.