European Journal of Molecular & Clinical Medicine

Background:The bleeding disorders are known to treating physicians since 16th century. Congenital bleeding disorders are found in all racial groups and have worldwide distribution but very limited information is available in developing countries. Deficiencies of congenital coagulation factors result in patients with bleeding disorders. Among all, hemophilia A (HA), hemophilia B (HB), and von Willebrand disease (vWD) are the commonest and are characterized by low levels of factor VIII, factor IX or von Willebrand factor (vWF), respectively. According to the World Federation of Hemophilia (WFH), 2015 around one of every 10,000 individuals are born with hemophilia A and roughly one of every 50,000 individuals are born with hemophilia B.