Online ISSN: 2515-8260

Keywords : idiopathic

Vocal cord paralysis and its etiologies: A retrospective study in tertiary care hospital

Dr. Amit Kumar Sharma,Dr. Mahesh Kumar,Dr. Stuti Shukla, Dr. Rakesh Kumar Singh,Dr. SaritaKumari Mishra

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 1, Pages 1517-1521

Background: Vocal cord paralysis (VCP), defined as the loss of normal adduction/abduction
caused by a lesion distant from the cords, result from neural injury to the recurrent laryngeal
nerve. Present study was aimed to study various etiologies of vocal cord paralysis at a tertiary
Material and Methods: Present study was hospital based, retrospective observational study,
conducted patients with vocal cord palsy confirmed with endoscopy.
Results: In present study, 52 cases were of vocal cord paralysis were evaluated in detail.
Majority were from 41-60 years age group (53.85%) followed by 41-60 years age group
(28.85%).Male patients (57.69%) were more than female (42.31%). Common symptoms
noted in present study were dyspnoea (75%), hoarseness of voice (55.77%), dysphagia +
dyspnoea (30.77%) & dysphagia (25%). Majority of cases had unilateral vocal cord palsy
(92.31%) as compared to Bilateral (7.69%) vocal cord palsy. Among cases left (61.54%) side
involvement was common than right (30.77%). In present study, various neoplasms (thyroid,
bronchogenic, esophageal) & post surgical (thyroidectomy, esophagectomy) were most
common etiology in 26.92% patients each. Other etiologies were idiopathic causes (17.31%),
neck nodes/cervical metastases (11.54%), mediastinal masses/lymph nodes (5.77%), CNS
causes (5.77%), cardiovascular (3.85%) &blunt Trauma (1.92%).
Conclusion: Vocal cord paralysis was common in males, at 5th& 6th decade & it was
unilateral in majority of cases. Common causes of vocal cord paralysis are neoplasm, postsurgical
& idiopathic.

A New Onset Recurrent Myositis Idiopathic Orbital Inflammation in Adult Male Patient : A Case Report

Desti Priani; Yunita Mansyur; BatariTodja Umar

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 3, Pages 2064-2069

Idiopathic orbital inflammation (IOI) is a benign, non-infective clinical syndrome
characterized by inflammation of the orbit without identifiable local or systemic disorders. Orbital
myositis is one classification of IOI and rare in adult male patients. In this article, we report a 41-yearsold
male who presented to the eye clinic with swollen, redness, pain, chemosis, and squints on his left
eye 2 weeks ago. He had a history of recurrent swollen on his left eyelid and self-treated with
methylprednisolone. Visual acuity on right and left eye were 20/25 and 20/30, respectively. The
intraocular pressure on the right and left eyes were 18 mmHg and 24 mmHg, respectively. No
abnormality in the fundus examination. There was a restriction on the left eye movement to all gaze,
and the eye was fixed to the superior temporal direction. Head MRI-scan showed hypertrophy of the
lateral and medial rectus muscles on the left eye without any other abnormality in the intracranial
cavity. The laboratory examination showed leukocytosis, neutrophilia, lymphopenia, normal thyroid
function, low C-Reactive Protein level, and a negative result for the antinuclear antibody test and antids-
DNA test. The patient was diagnosed with myositis of idiopathic orbital inflammation and was
treated with a high dose of methylprednisolone 1 mg/kg BW/day. Two weeks later, the patient had
improvement in his eye movement and the swollen was resolved. The treatment is still ongoing. Finally,
we can conclude that comprehensive evaluation and treatment with high-dose corticosteroid results in a
better outcome in an adult male patient with myositis IOI.