Keywords : diabetic peripheral neuropathy andtype 2 diabetes mellitus
The association between neutrophil lymphocyte ratio, vitamin (D) deficiency and development of peripheral neuropathy in type 2 diabetic patients
European Journal of Molecular & Clinical Medicine,
2021, Volume 8, Issue 3, Pages 1979-1991
Background/Aims:Some studies had suggested that neutrophil lymphocyte ratio (NLR) levels grow with
the increase of nerve conduction velocity (NCV). Recently, several studies found that vitamin (D)
deficiency can cause the risk of diabetes mellitus (DM) and its complication including neuropathy.The
aim of our study is to evaluate the association betweenNLR, vitamin (D) deficiency and development of
peripheral neuropathy in type 2 diabetic (T2DM) patients.
Methods: In cross sectional study we selected a total of 60 T2DM patients.All patients underwent nerve
conduction study (NCS). Then we divided them according to the results into two groups, 45 patients with
DPN and 15 patients without DPN as a control group.DPN group wassubdivided according to NCS
results into three groups,11 patients with mononeuropathy,4 patients with mononeuropathy multiplex
and30 patients with polyneuropathy. We evaluated the effect of DPN in these patients as regarded NCS
results on HbA1c levels, NLR and vitamin (D) levels.