Online ISSN: 2515-8260

Keywords : diabetic neuropathy

Dry eye disease in type 2 diabetes mellitus: association with diabetic retinopathy and neuropathy

Suchitra Panigrahi, Sandhyarani Pati, Bidisha Mahapatra, Deepak Dash, Swarnamayee Baskey, Ramakristna Sahu

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 2480-2487

Aim- To study the prevalence of dry eye disease(DED) and its association with diabetic retinopathy (DR), diabetic neuropathy (DN) and other metabolic parameters in patients with type 2 diabetes mellitus. Materials and methods- Dry eye disease was assessed in 102 patients with type 2 diabetes mellitus using OSDI (Ocular Surface Disease Index) score, tear break up time(TBUT) test and Schirmer’s test. All the subjects underwent indirect ophthalmoscopy, DN screening was done based on Revised NDS score, DR was graded according to Early Treatment Diabetic Retinopathy (ETDRS) criteria. The relation of DED with status of diabetic retinopathy, peripheral neuropathy, dyslipidemia, metabolic control and duration of disease was also assessed. Results- The prevalence of dry eye disease was 37.2%.We observed a significant associationof dry eye disease with diabetic retinopathy (p=0.017) and diabetic neuropathy(p=0.019). Conclusion- As the prevalence of DED among diabetics is high and diabetic retinopathy and neuropathy are often found to be associated with DED, therefore, along with screening for DR and DN, assessment of dry eyes should be routinely included in patients with diabetes in ophthalmology clinics.


Ahmed Magdy Alshimy; Nawal Abou Shady; Amira Mohamed El Gohary; Khalid Taha Yassin Turky

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 9, Pages 269-275

Objective: Investigate high tone therapy effect on neurophysiological measures and function outcome in diabetic neuropathy. Methods: Forty patients assigned randomly into high tone therapy and conventional therapy groups. Patients assessed by neurophysiological studies for median and sural sensory nerves and activities of daily living assessed by Katz Index of Independence. Results: Neurophysiological measures for median and sural sensory nerves were significantly improved in high tone therapy group but not in conventional therapy group. The function outcome was significantly improved in both groups with the best results for high tone therapy group. Conclusion: High tone therapy was able to improve neurophysiological measures and function outcome in diabetic neuropathy patients.