Online ISSN: 2515-8260

Keywords : Antioxidant activity


POTENTIAL ANTIOXIDANT ACTIVITY FROM METHANOLIC EXTRACT OF HALOPHILA OVALIS

Amba. E; Gayatri Devi. R; Pitchiah Sivaperumal

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 8, Pages 1786-1795

Seagrasses play an  important ecological role in fisheries production, sediment buildup and stabilization. It has direct value to people as food, feed, green, manure, and medicine. Seagrass species have been found to be potential sources of antibacterial, antifungal and anti-inflammatory agents as well as anti-cancer substances by phytochemical investigations. The main aim of this study is to prepare Halophila ovalis extract powder and to determine the antioxidant activities of methanolic plant extract.
The antioxidant activity of methanolic extract of Halophila ovalis was investigated by TAA, DPPH and H2O2 assay.
The study revealed that methanol extract of Halophila ovalis has greater antioxidant activity. Flavonoid content was found highest in methanol extract of Halophila ovalis. It showed high radical scavenging activity.

PHYTOCHEMICALS INVESTIGATION OF ANTIOXIDANT, ANTICANCER ACTIVITY OF DRY FRUIT EXTRACT OF FICUS CARICA LINN IN EXPERIMENTAL ANIMALS

HAQUE MUDABBIRUL , SHIRSAT MRUNAL KRISHNARAO, KAYANDE NANDU, AEJAZ AHMED

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 1420-1429

The antioxidant and anticancer activity dry fruit extract of ficus carica linn investigated against free radical scavenging activity (RSA) [reactions with 1,1-diphenyl-2-picrylhydrazyl radical (DPPH) and anticancer activity against Dalton’s ascitic lymphoma cell line and assessment of the influence of extracts on the enzyme xanthine oxidase (XO), and Fe3+ reducing ability. Antitumor activity was studied on swiss albino mice at various dose such as 250, 500, and 1000 mg/kg, body weight. The experimental parameter used were tumor volume, tumor cell count, viable tumor cell count, mean survival time and increase in life span to assess antitumor activity. The extract was administered orally for 14 consecutive days to tumor bearing group of animals. It increases the life span of DAL treated mice and restores the hematological parameters as compared with the DAL bearing mice in dose dependent manner. The study revealed that the extract of ficus carica (EFC) showed significant antitumor activity in tested animal models. 

Antioxidant Activity Of Aqueous Extract Of Plantain Flower Bract

Methaq Hadi lafta

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 6, Pages 413-417

Background: The objective of this study is to find out the antioxidant activity of plantain flower bract of Musa Paradisiaca. Musa paradisiaca is one of the most important fruit crops with some medicinal benefits which is beneficial to cure some diseases like diabetics, dysentery, ulcer etc. and it also have some antioxidant properties.
Method: Oxidation is a process that produces free radicals which damage cells in human beings by inducing oxidative stress so that the antioxidant properties are used to remove or fight against the free radicals. The antioxidant activity was found out by DPPH (1, 1-diphenyl-2-picrylhydrazyl) free radical scavenging method and also, we have seen total antioxidant capacity assay. Results: Because this plantain flowers bract has high content of phenolic compounds and other phyto chemicals which contributes to the antioxidant activity. Conclusion: This DPPH free radical scavenging method was done by using methanol extract and the DPPH assay proved that the bract has potent antioxidant activity and it shows the 168.04 IC50 μg/ml for scavenging activity and 129.29 IC50 μg/ml for total antioxidant capacity assay.

Estimation Of Phenolic Compounds And Evaluation Of Their Antioxidant Activity Of Some Parts Of The Orange Plant (Citrus Sinensis L.)

Iman Mohsin Kadhom; Nagham Saddon Ibrahim; Najim Abdullah Al-zubaidy

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 3, Pages 4811-4822

Orange fruits were collected from one of the gardens of Baqubah / Diyala / Iraq in January of 2020, while samples of leaves and flowers were collected in March of the same year, for the purpose of completing the research procedures. The present study aims to estimation of phenolic compounds and evaluation of their antioxidant activity of the extract of some parts of the orange plant. The results show a variation in the parts of the orange plant in their content of phenolic compounds. Moreover, the statistical analysis pointed to the presence of significant differences at the probability level of P <0.05 among the parts of the orange plant, in Total Phenolic Content (TPC) and Total Flavonoid Content (TFC). The leaves are superior in their (TPC) which record the highest in comparison with the juice, which recorded the 1-concentration of 145.71 mg( GAE) .g. Though the highest (TFC) in the mesocarp of fruit is 1-lowest (TPC) 57.18 mg( GAE) .gin the juice, which gave the 1-compared to 5.81 mg.Querecetin. g 1-mg Querecetin .g 11.14lowest (TFC).
On the other hand, the result of statistical analysis showed significant difference among the parts of orange plant at the probability of P <0.05 in antioxidant activity. The result showed that the highest antioxidant activity, detected by using the DPPH scavenging . While the lowest value of the free radicals DPPH 1-test of the flowers is 2.64 mg. mLwas obtained from exocarp. The statistical analysis 1-inhibition, which was 0.86 mg. mLresults indicated a positive correlation among the (TPC), (TFC) and the antioxidant activity of DPPH free radical test with value of 0.385 and 0.484 respectively.