European Journal of Molecular & Clinical Medicine

Background:Stroke was the second most frequent cause of death worldwide in
2012,accounting for 7.1 million deaths. as data availablefrom Indian subcontinent is
scrace in relation to Hyper homocysteinemia as a potential risk factor in ischemic stroke
The present study is designed to measure theplasma homocysteine levels in patients
presenting with ischemic strokes and correlate with the levels in age and sex matched
controls.
Materials and Methods: This study is a case - control prospective study. The present
study was done on 80 patients with ischemic stroke admitted in local area hospital 30 –
35 age and sex matched controls were recruited for the study. Plasma fasting total
homocysteine (tHcy) levels were measured by chemiluminiscence immunoassay.
Students‘t’ test and chi-square test were used to analyse data.
Results: The total homocysteine (tHcy) were significantly higher in patients with stroke
compared to controls (19.94±4.73 Vs 7.85±4.56, p-value is <0.001). The tHcy levels were
significantly high in smokers compared to non-smokers (31.11±2.44 Vs 12.22±3.63, pvalue
is <0.05), patients with hypertension compared to normotensive patients
(32.09±1.04 Vs 15+3.21, p-value is <0.02), patients with diabetes mellitus compared to
patients not having diabetesmellitus (23.22±4.39 Vs 12.87±2.99, p-value is <0.05),
patients with dyslipidemia compared to patients not having dyslipidemia (31.12±3.99 Vs
12.93±2.23, p-value is <0.05). Patients with no risk factors compared to controls
(14.11±4.38Vs 8.76±1.25).
Conclusion: Hyper homocysteinemia emerged as an important risk factor for ischemic
stroke. A strong positive correlation was also observed between hypertension, diabetes
mellitus, smoking dyslipidemia and tHcy levelsin thepresent study.

India is fast becoming a necessary tourism location in the world. International arrivals
contacted 5 thousand yearly. The initiative "Astonishing India" which include the best
that India has to offer to the vacationers has now produced all over the world interest. The
proactive programs of the Authorities of India are promoting tourism in India. Andhra
Pradesh is the leading state in the nation in bring in an optimum wide array of residential
vacationers. In 2012, 157 million residential tourists observed Andhra Pradesh. This notes
an improvement of 14% over 2011. Telangana topographically and typically possesses a
range of tourist attractions featuring hills, creatures, jungles, barrier and also holy places.
This place has a wealthy cultural heritage and is identified for its very own bountiful file,
type as well as likewise society. This region has all the required top qualities for becoming
an effective site visitor location in India. The climate is normally tropical. This paper
briefly provides a case study on andhra pradesh and telangana states towards cultural
tourism.