Online ISSN: 2515-8260

Keywords : General Anaesthesia


A RANDOMISED CONTROLLED STUDY OF TRACHEAL EXTUBATION RESPONSE FOLLOWING NITROGLYCERINE (NTG) SUBLINGUAL SPRAY IN HYPERTENSIVE PATIENT

KORI, ANIL RAI, PARTH MISHRA, SHAILESH AJMANI TEJINDER JAIN, ABHILEKH AGARWAL, ADITYA BATRA, MAHIMA TAGALPALLEWAR, AMEYA

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 7, Pages 99-110

The prospective randomized open controlled study was done to compare tracheal extubation response following nitroglycerine (NTG) sublingual spray in hypertensive patients

Comparison of Atracurium versus Cisatracurium Regarding Onset Time, Intubating Conditions and Haemodynamic Parameters and Duration of Action

Nikita Baser, Vijay kumar, Shilpa Sharda, Neetu Maurya

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 5, Pages 132-137

Background:Endotracheal intubation is an integral part of the administration of general anesthesia during the surgery. Neuromuscular blocking agents facilitate general anaesthesia. cisatracurium having lack of histamine release, which provides better cardiovascular stability in comparison to atracurium. To compare of atracurium and cisatracurium onset time, intubation conditions, hemodynamics and duration of block.
Materials and Methods: The present study was a prospective randomize, conducted in the Department of Anaesthesia, Pacific medical college and hospital Udaipur, Rajasthan. Total 70 ASA Grade I/II patients in the age group of 18-60 years posted for elective surgery required general anesthesia were selected in this study.  Patients were divided into two groups of 35 each. Group A patients received atacurium 0.5 mg/kg as loading dose while Group B cisatracurium 0.2mg/kg, The onset time,intubating conditions hemodynamic parameters and duration of action were noted.
Results: Cisatracurium have rapid onset (p<0.001) and long duration of action (p<0.001) and stable mean arterial pressure (p<0.001) and better intubating conditions (p=0.04.).
Conclusion: Cisatracurium provides rapid onset, excellent intubating conditions, long duration of action and good haemodynamic stability in comparision to atracurium.

EFFECTIVENESS OF SPINAL ANESTHESIA VERSUS GENERAL ANESTHESIA FOR OPEN CHOLECYSTECTOMY: AN INSTITUTIONAL BASED STUDY

Mamta Damor, Rajendra Verma, Hemant Jingar, Rekha Roat

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 4, Pages 1659-1665

Introduction: Cholecystectomy is performed either as an open or a laparoscopic route. Despite of a number of peri-operative and post-operative benefits of laparoscopic cholecystectomy, the traditional and invasive open cholecystectomy is still in frequent practice for various reasons. Therefore, this study was conducted to compare the effectiveness of SA for open cholecystectomy versus GA with respect to reducing post operative pain, analgesia requirement, respiratory complications and length of hospital stay.
Materials and Methodology: One hundred and forty patients were allocated randomly into two groups—SA group (spinal anaesthesia group, n = 70) and GA group (general anaesthesia group, n =70). And the two groups were divided as SA group underwent open cholecystectomy under spinal anaesthesia whereas GA group had undergone it under general anaesthesia.
Results: Out of all the 140 patients, 70 patients were allotted in each group, there were 120 females (85.85%) and 20 males (14.17%). Their age mostly ranged between 18 – 70 years, with a mean of 42.35 ± 12.66 years. There was no statistically significant difference between both the study groups with respect to age, sex distribution, body mass index (BMI) and ASA physical status. Intra-operatively, bradycardia and hypotension were more common in the SA group. Bradycardia less than 50/ min in 12 patients (16.66%) were treated by atropine 0.6mg IV. Bradycardia was the only side effect noted in both groups.
Conclusion: Since the conventional use of general anaesthesia in open cholecystectomy, this study displays that spinal anaesthesia is also a recommended alternative. It is therefore safe and more effective than general anaesthesia in providing prolonged post-operative pain-free interval, less analgesic/ opioid requirement and no reported respiratory problems.

A comparison of clinical performance between the I-Gel and the Baska mask in spontaneously ventilating anaesthetised patients: A prospective randomized study

Dr. Faraz Ahmed, Dr. Jayashree B Patil, Dr. Sneha Rajur, Dr. Bhagyashri V Kumbar

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 2, Pages 1638-1644

Supraglottic Airway devices (SAD) have now become a fundamental tool for ventilation, oxygenation and delivery of anaesthetic gases in modern anaesthesiology. The advent of newer generation of SADs has resulted in their extended use. Baska mask and I Gel being newer generation SADs are vastly being used due to their specific designs for ease of securing the airway, better ventilation and higher patient safety. After institutional ethical committee clearance, a prospective randomized comparative study was conducted. 60 patients of age group 18-60 years of ASA grade I and II undergoing elective surgeries under GA were included. Patients were randomized into 2 groups, Group B (Baska mask group) and Group I (I Gel group) with 30 patients in each group. The ease of insertion (p value 0.035), insertion attempts (p value 0.04) and the time taken for insertion (p value <0.001) were significantly better with I Gel compared to Baska mask. Both the groups were comparable in terms of postoperative pharyngolaryngeal morbidities.

HEMODYNAMIC STABILITY DURING LAPAROSCOPIC APPENDECTOMY UNDER SPINAL ANAESTHESIA IN COMPARISON TO GENERAL ANAESTHESIA

Dr. VeerendraPatil, Dr. NagarajMalladad Dr. Madhusudhan BV

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 4, Pages 1494-1497

Laparoscopy has revolutionised surgery and management of the patient with marked decrease in morbidity and post-operative complications. Initially, these procedures were done using only General Anaesthesia. However, now with the introduction of Spinal anaesthesia and after learning its advantages, surgeons are slowly beginning to gravitate towards this mode of anaesthesia. Sixty three patients who were admitted in the hospital for appendicitis participated in this Randomized controlled trial conducted in a tertiary care hospital in India. Thirty three patients were randomly included in Group A (undergoing laparoscopic surgery under Spinal Anaesthesia) and thirty patients in Group B (undergoing laparoscopic surgery under General Anaesthesia). The mean values of Systolic and diastolic pressure was found to be significantly higher in patients who were administered General anaesthesia and no change in the respiratory functions was observed following administration of either Spinal or General anaesthesia. Laparoscopic surgery under Spinal anaesthesia is a viable and safe alternative as compared to General anaesthesia. The recovery rates and the satisfaction reported by patients is also better. Spinal anaesthesia also helps in maintaining better haemodynamic stabilization.

Case Preferences In Choosing Consious Sedation Versus General Anesthesia Amongst Pediatric Dentists: A Research Survey

Dr. Sravanthi Veeramachaneni; Dr. Sandeep Dande; Dr. Tulluru Ajay Mohan; Dr. Mohammed Muzammil Khan; Dr. DilipKumar. S; Dr Shilpi Verma; Dr. Priyanka Parhad

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 1, Pages 1252-1257

Aim: Purpose of our research was to assess the preference of pediatric dentists to carry out
treatment with either conscious sedation or with general anesthesia.
Methodology: 50 children were selected for your study who did not have any previous
medical conditions. Patients requiring complete dental treatment were treated under GA,
those requiring one or two procedures were under conscious sedation. The two groups of
patients were evaluated in terms of vital signs, duration of the treatment procedure, patient
behavior, recovery time and comfort experienced by the dentists and the anesthesiologists.
Results: Dentists in sedation group were anxious, uncomfortable and restless during
implementation of dental treatment. During dental procedure under sedation, some
interruption has been noted in few cases such as vomiting during the procedure (3 cases).
Those who vomited, during the procedure, their heads were turned to one side, the
procedure was discontinued immediately (to prevent aspiration), and the patients were
referred for treatment under GA.
Conclusion: Dental treatment under CS can be successful with little or no complications if
the cases are well selected by qualified trained dentist.