European Journal of Molecular & Clinical Medicine

Introduction: Physical and mental health have a bidirectional relationship that influences
one another. Several clinical studies have shown that metabolism and emotional state may
share comparable pathways. Although metabolic syndrome and mood disorders often
manifest themselves in adulthood, the likelihood of acquiring these illnesses is influenced by
social and economic conditions in childhood, such as childhood maltreatment, neglect, and
family dysfunctions.
Aim and objectives: To examine the association between childhood adversity and
components of metabolic syndrome in patients with mood disorders and to test whether
specific types of childhood adversity and type of mood disorder interact to worsen metabolic
outcomes.