Online ISSN: 2515-8260

Keywords : pain


Evaluation of the effectiveness of gabapentin in the management of postoperative pain after total hip arthroplasty

Dr. Karunakar Dwivedi, Dr. Ashutosh Singh, Dr. Manish Maheshbhai Khokhar

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 2, Pages 1482-1486

Background: It was well reported that gabapentin has a role in the management of neuropathic pain. However, substantial evidence for the same was sparse.
Objective: The present study was undertaken to evaluate the effectiveness of gabapentin in the management of postoperative pain after total hip arthroplasty.
Materials and methods: A total of 50 patients diagnosed with sepsis and aged more than 18 years including both males and females were part of the study after obtaining the written, voluntary informed consent. Unwilling participants were excluded from the study. Patients with any severe complications were also excluded from the study.
Results: The majority of the participants were males with 60 % and females were 40%. The majority of patients were having pain scores of 7-9 before the intervention in the control group. The majority of the patients are in pain scores of 7-9 after ibuprofen in the control group. Table no 5 presents the distribution of the intervention group participants according to the pain scores after intervention. The majority of the patients were in pain scores of 1-3 after the administration of gabapentin.
Conclusion: The study results confirm that gabapentin has a significant effect on the management of pain after the surgery of the knee and hip. The study recommends further detailed study in this area to recommend gabapentin in the management of pain.

Pre and Post Incisional Local Infiltration of the Levobupivacaine in Conventional Laparoscopic Cholecystectomy

Naresh Kumar, Shiv Kumar Bunkar, Dinesh Kumar Sharma, Hari Om Dhaker

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 2285-2293

Background: Laparoscopic cholecystectomy (LC) has become the gold standard for treatment of benign Gall Bladder disease. Pain after laparoscopic surgery though primarily visceral, often affecting the sub diaphragmatic region and often referred to the right shoulder region, also has a parietal component which occurs at the trocar site. The present study was planned to evaluate the effect of combined port site levobupivacaine administration before and after surgery for patients who underwent Laparoscopic cholecystectomy.
Material & Methods: This was a hospital based prospective randomized double blind comparative study done on 100 patients undergoing elective laparoscopic cholecystectomy surgery at Jawahar Lal Nehru Hospital, Ajmer, after approval from ethical committee. The study population were randomly divided into two groups A (Preincisional) and B (Post incisional) with 50 patients in each group using computer generated tables of random numbers. The primary outcome variable was to compare pain (visual analogue scale [VAS]) score. The intensity of post-operative pain was recorded for all the patients using VAS score at 3, 6, 12, 24 h after surgery (mean of all VAS scores).
Results: Our study showed that mean age of patients in group A was 43.20 years and 41.16 years in group B, which was statistical non-significant (P=0.435). There was significant difference in the mean VAS scores between the two groups up to 12th hour postoperatively. There was statistically lower VAS score in group A as compared to group B postoperatively up to 12 hour at 24th postoperative hour there was no significant difference in VAS score in both groups. The mean duration of analgesia was 164.94 ± 27.37 min in group A with a range of 95 to 210 min., while in group B, the mean duration of analgesia was 121.42 ± 14.81 min. with a range of 85 to 145 min, which was statistically longer in Group A as compared to Group B, (p value < 0.0001). Mean number of doses required in group A was 1.70 ± 0.46 and in group B was 2.38 ± 0.49, which was statistically higher in group B (p value <0.0001). In group A total amount of tramadol required in 24 hours was 170.00 ± 46.29 mg in comparison to group B where it was 238.00 ± 49.03 mg (p value <0.0001).
Conclusion: We concluded thatlevobupivacaine can be safely used as local anesthetic infiltration for postoperative pain relief following laparoscopic cholecystectomy surgery.

The Effectiveness of Dry Cupping and Hot Pack in Pain Relief and Reduce Functional Disability on Non-specific Low Back Pain

Azira Iqlima Razali, Bsc; Lee Ai Choo, PhD

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 3, Pages 2796-2810

The objective of this study was to identify the effectiveness of dry cupping and hot pack on pain relief and reduce functional disability for patients with non-specific low back pain. A total of 39 patients with non-specific low back pain from Sultan Idris Education University, Malaysia who fulfilled the inclusion criteria were chosen as participants using purposive sampling methods. The participants were randomly assigned equally (N=13) into dry cupping group, hot pack group and control group. Dry cupping group received a session of treatment in a week, hot pack group received twice a week of treatment session and control group had no treatment, but the participants were allowed to continue their previous treatment. Numerical Pain Rating Scale (NPRS) was used to measure pain intensity and Oswestry Disability Index (ODI) was used to measure functional disability before and after the intervention for all three groups. Data was analyzed using one-way ANOVA with significant level was predetermined at p<0.025 prior to study. The study findings indicated that both dry cupping group and hot pack group showed significant improvement on pain relief (p=0.001) and functional disability (p=0.001) after completing the interventions when compared to control group. Therefore, both dry cupping and hot pack were found to be effective interventions for pain relief and reduce functional disability among patients with non-specific low back pain. Health professional practice are suggested to include dry cupping therapy as another choice of treatment in treating patients with non-specific low back pain.

Postural Assessment Of Rural Water Fetcher Using Ergonomics

Sonali P. Patil; Keshav K. Sangle

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 6, Pages 427-433

REBA and RULA Ergonomic tools are used for evaluation and ergonomic assessment while carrying, handling, lifting and shifting the load. For evaluation of complex manual water fetching activities a RULA and REBA ergonomic tool is used .In this study of water fetching activities maximum women from rural area were participated. Based on this ergonomic tool observation, water fetching activities of women while water fetching, video recordings and photographs were taken. The reviewed literature, postural activity guidelines are proposed for summarizing analysis of water fetching women’s activity and discomfort has been reported. The basic aim of water fetching study is to make assessment of the level of exposure of ergonomics in various water fetching activities. Another objective of the water fetching activities is to find the level of exposure and musculoskeletal disorders in different body segment and gives the corrective steps to reduce the health risk in the water fetching activity.

ORTHODONTICS AND TEMPOROMANDIBULAR DISORDERS

.Dr.K.C. Subhiksha; Dr. Gnanashanmugam; Dr. Kannan Sabapathy

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 4, Pages 1732-1736

Temporomandibular disorders are considered as the main source of pain in the head and neck region which is of non- dental in origin. Its etiology is multifactorial and its pathogenesis has not been completely understood. The interest in the relationship between occlusal factors, orthodontic treatment and TMD has increased over the years. Hence the aim of this article is to review ten association of TMD and orthodontics from the available literature.

TO THE ISSUE OF MEDICATION THERAPY OF CHRONIC PAIN SYNDROME IN PATIENTS WITH TERMINAL RENAL INSUFFICIENCY RECEIVING THERAPY FOR CHRONIC HAEMODIALYSIS

Javokhir Khalmukhamedov; Botir Daminov; Yorqin Rasulev

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 2401-2409

A growing number of publications in the literature show that chronic pain is
also characteristic of patients with terminal renal failure (TRF). The disease tends to be
moderate or severe and affects virtually all aspects of health and quality of life.
Unfortunately, there is a lack of clinical and research focus in nephrology, and TAPN pain
is poorly understood. The article reflects the main aspects of the problem of pain
medication therapy for patients with terminal renal insufficiency receiving chronic
hemodialysis. The main pathophysiological mechanisms of medication influence on kidney
structures are described.

The Role of Pulsed Radiofrequency for Greater and Lesser Occipital Nerves in the Treatment for Migraine

Rida Alkaabi; Haider Shafi Hussein

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 104-109

Background: Migraine pain is a primary headache disorder characterized by recurrent headaches that are moderate to severe. Objective: To evaluate the effect of noninvasive pulsed radio frequency (pulsed RF) in Migraine. Methods: In a prospective study of the intervention performed in adult population with Migraine (Diagnosed by specialists) carried on (30) patients undergone pulsed RF for greater and lesser occipital nerves to control recurrent migraine not responding to conventional treatment (resistant) in a period from Jan. 2017 to Jan 2019 in Al Safeer Hospital for surgical specialties and Alkafeel Hospital for surgical specialties both in Karbala / Iraq. The patients got in prone position under local anesthesia with goal positions with the target sites obvious out using anatomical breakthroughs and the position of greatest ache. Pulsed RF by RF needle to the affected side to reach greater and lesser occipital nerves then got 3 sessions (each for 3 minutes, temperature 42 C, voltage 42 V, resistance with 100 Ohms, Current with 230 mA) Patients monitored post-operatively for 2 hours then discharged. Follow up at intervals of 30 days, 6 months and 1 year by phone call or direct interview to assess the post procedure pain scale. Result: Significant pain relieve by means of no or little pain medication and actual life pattern change and performance in 1-year post procedure. Conclusion: A single trial of pulsed RF is effective for pain reliever.

ASSOCIATION BETWEEN FIRST DENTAL VISIT AND PAIN IN CHILDREN -A RETROSPECTIVE STUDY

SarojiniRamyaPillay .; Jessy P; Remmiya Mary Varghese

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 1587-1596

Oral health is a vital part of overall infant health.An early age between 6 months to 12 months dental visit is important in rendering prevention,intervention and parental counselling regarding oral health. Pain is an unpleasant sensory and emotional experience associated with actual potential tissue damage according to internal association for the study of pain. Aim of the study is to assess the association between age of the first dental visit and pain in children. A retrospective cross-sectional study was conducted using the patient records from the Department of pedodontic, Saveetha Dental College,visited from February 2019 to February 2020.The children with first dental visit without the past dental history were collected and from which whosoever first visit with chief complaint of pain data were gathered . The collected Data was then subjected to statistical analysis using spss version 20.0.Overall prevalence of chief complaint of pain during first visit was (96.5%). Among first dental visit with pain about 47.2 % was seen in the age of 6-8 years while the least was (14.0%) seen at the age of 11-13 years.The results proved that many parents were unaware about the right age of the child first dental visit.Most of the parents bought their children to the dentist after their child experienced or suffered from pain.There is a need to raise awareness about the importance of oral health care of their children sensitively at the budding stage of life

EFFECT OF WET CUPPING USE AMONG PATIENTS COMPLAINING OF PAIN ATTENDED IN THE HIJAMA CLINIC MAKKAHAT SAUDI ARABIA 2019

Waleed Ibrahim Sindi, Abdulrahman Ahmed Alzhrani, Abdullah Marzooq Al Harbi, Fuad Shaker Rashad Zainy, Adnan Rubayan Obaid Alotaibi, Saleh Mousa Alzahrani Amna Adam Bakur Hawsawi, Sabah Saeed Abdallah AL-yateem, Majed Saad Siraj Alharthi, Safran Ibraheem Alharthy

European Journal of Molecular & Clinical Medicine, 2019, Volume 6, Issue 1, Pages 205-215

Wet cupping is a traditional and alternative treatment that is still used to reduce patients’ pain in several Eastern and European countries. It has been proven effective and has an essential role in reducing pain and as a treatment for many diseases in past studies. Nowadays, there is a growing interest in the field of complementary and alternative medicine (CAM). This discipline includes a diverse set of approaches used for prevention and treatment of many diseases. Several benefits of CAM have been proven, and it may be considered an effective modality for disease prevention, treatment of non-communicable diseases and for improving the quality of life of individuals with chronic medical conditions.2 Many patients who may not be satisfied with the outcomes of modern medicine, particularly those with chronic diseases, may be satisfied with the outcomes of CAM. Pain is the most common reason for seeking therapeutic alternatives of conventional medicine. Cupping, wet or dry, is an ancient treatment, which was broadly utilized in several communities, and it was recommended by the Islamic society.
Aim of the study: The study aimed to assess the effect of wet cupping use among patients complaining of pain attended in the Hijama clinic in Makkah City at Saudi Arabia.
Method: A retrospective records review study was conducted using medical records of patients who attended in the Hijama clinic at Makkah, KSA from January 2019 to December 2019. Our total, 200 patients attended the clinic during the year 2019. Out of those patients, 120 were complaining of pain and were included in the study. The Chi-square test and Multivariate logistic regression were used to measure the association between the various socio-determinants and the wet cupping use.
 Results: A chi-square test of independence was performed to determine the association between the frequency of WCT use and the main complaint, independence was performed to determine the association between the frequency of WCT use and the main complaint. There was a statistically significant association between them, Chi-square X2 =86.663, p=0.001.
 Conclusion: Wet cupping has positive effects on reducing pain. There are promising effects in favor of using wet cupping for improving quality of life of patients with chronic conditions, cupping is recommended as a complementary treatment modality for chronic medical conditions, especially pain .