European Journal of Molecular & Clinical Medicine

In every century, few invisible infectious diseases create an alarm to the entire world and which leads to extermination of the population. In 1918 and 2019, the world has tackled truculent diseases such as mother of all pandemic Spanish flu and COVID 19. The mortality rate of Spanish flu was greater than in the first world war. After 100 years’ same history was repeated in 2019 through COVID 19.  Suddenly a huge number of pneumonia cases were reported in the end of 2019 in Wuhan, China. These two outbreaks make medical, social and financial burden to the entire world. This kind of sudden pandemic breaks mental health and creates panic, anxiety and depression. Pharmaceutical preventive measures are not supported during both pandemics which was rectified by non-pharmaceutical preventive steps like lockdown, quarantine, wearing facemask and gloves, washing hands and applying sanitizer, follow the social distancing, closing cinema hall and schools, avoiding mass gathering in 1918and 2019-2020. The main objective of this review is to compare and summarize the concepts of both pandemics and how the people of the world need to come together and fight against common enemies, to warrant that we have the best scientific resources necessary to bring this outbreak to an end.

Multiple myeloma is a hematological malignancy of the plasma cells with evidence of bone marrow infiltration. It is accompanied with extramedullary plasmacytomas. There are a variety of possible treatment options, but this review focuses on allogeneic bone marrow transplantation for the treatment of multiple myeloma. Allogeneic bone marrow transplant is commonly known as stem cell transplantation. From the review, the results suggest that this can be used as a treatment option for fit young individuals as compared to older individuals. It also shows better results during the early stages relative to the later stages with poor prognosis. In conclusion, allogeneic bone marrow transplant can help treat multiple myeloma, but it depends on factors such as age, stage of cancer, fitness of the individual.