European Journal of Molecular & Clinical Medicine

Miller Fisher syndrome(MFS) is a likely variant of Guillain-Barre syndrome(GBS). Here, we present a case with peculiar demonstration of MFS as per the patient was found to have areflexia , ptosis left right distal with absent positional ,vibration sense and positive Romberg’s signs. There was history of pricking sensation in both Upper limb/Lower limb and swaying while walking, more towards the right. It was concluded as MFS from the clinical reports and the history taken. The infirm was started on methylprednisolone 1gm was given for 5 days followed by tapering dose of oral steroids along with Physiotherapy. Patient improved during the course in hospital and became stable. This event, point out the facts of a atypical disorder, which able us to limit the discrepancies to work out rapidly and properly handle such infirm. The anti GQ1b immunoglobulinG antibody is a definite marker of Miller Fisher syndrome, thus helps in the diagnosis of MFS. This moreover shows the importance of taking the history and medical assessment.

Metabolic syndrome is a group of simultaneous conditions that expanding your risk of heart disease, stroke, and type 2 diabetes. These conditions include increased blood pressure, high glucose level, and abundance muscle versus fat around the abdomen or triglyceride levels. The objective of the study is to demographic, biochemical, obesity indices and angiographic profile (severity of CAD) of patients with coronary artery disease (CAD). A prospective and observational study involving a number of 971 patients who had undergone coronary angiogram (CAG) for the 18-month CAD assessment. In present study about half of population had significant abnormality on coronary angiogram. Amongst abnormal coronary angiogram about 50% of patients had single vessel disease. The FRS had positive correlation with severity of coronary artery disease and waist circumference. FRS and metabolic syndrome had critical contribution as score and risk factors with presence of and severity of CAD. To conclude it was suggested to incorporate FRS and components of metabolic syndrome for better management and risk stratification of coronary artery disease at large.