Online ISSN: 2515-8260

Keywords : ultrasound


Ultrasonography in diagnosis of congenital uterine anomalies in Haryana Population

Dr Meetu Agarwal Dr Rishu Malik , Devesh Kumar Sharma, Col (Dr) B K Mishra, Dr Nakul Gupta, Vijay Kumar Soni

European Journal of Molecular & Clinical Medicine, 2023, Volume 10, Issue 4, Pages 241-245

To assess the accuracy of ultrasound in diagnosis of congenital uterine anomalies.
Material & Methods: This study of uterine morphology is being done on 30 females to assess the congenital anomalies of uterus. The records have been taken from the Radiology department, Al Falah Hospital, Faridabad,Haryana.
Results: Appearance of the uterus by the Two Dimensional Ultrasound was normal in 16 patients, subseptate in 3 pateints, Unicornuate in 0, bicornuate in 6, small uterus in 1, agenesis in 2 and arcuate in 2 patients.
Conclusion : A significant proportion of congenital anomalies of uterus are diagnosed during investigations for infertility. Accurate diagnosis helps in the appropriate counselling of women about their potential reproductive prognosis for planning any intervention with a view to improve the reproductive outcome.

Concordance Between Cytological Bethesda And Ultrasound Based Ti-Rads Reporting Systems In Thyroid Nodules

Dr. Manmohan, Dr. Monika B. Gathwal, Dr. Chiranjeev Gathwal, Dr. Deepti Agarwal, Dr. Naveen Sharma, Dr. Swaran Kaur

European Journal of Molecular & Clinical Medicine, 2023, Volume 10, Issue 4, Pages 1409-1418

Thyroid nodules are common entities, frequently discovered in clinical practice, either during physical examination, but also incidentally, during various imaging procedures. They are clinically important primarily due to their malignant potential. The literature indicates that the incidence of nodules is around four times higher in women than men.
Material and Methods : A total of 90 patients with thyroid nodules which were referred to Department of Pathology and Radio-diagnosis and underwent USG guided FNAC and TIRADS scoring were included. USG guided FNAC were examined and categorized according to Bethesda system. The Bethesda categories were correlated with TIRADS scoring in all 90 cases and with histopathological findings in 22 cases.
Results: A total of 90 patients were included out of which 83 were females. These thyroid nodules are predominantly found in females with right lobe preponderance in approximately 50% cases and in third–fifth decade of life. A total of 14 were categorized under TIRADS 1, 25 were categorized under TIRADS 2, 6 were categorized under TIRADS 3, 29 were categorized under TIRADS 4 and 16 were categorized under TIRADS 5. Out of the 90 nodules, 46 were categorized under Bethesda II, 6 were categorized under Bethesda III, 21 were categorized under Bethesda IV, 7 were categorized under Bethesda V and 10 were categorized under Bethesda VI. Proportion of risk of malignancy as TIRADS 2, TIRADS 3, TIRADS 4, and TIRADS 5 were 4.0%, 83.3%, 82.8% and 87.5%, respectively. In the present study, 86.36% sensitivity, 84.78% specificity, 84.44% PPV, and 86.67% NPV derived. Significant association was noticed between TIRADS and Bethesda system of classification (P < 0.001). On Histopathological diagnosis of 22 thyroid cases, sixteen out of 22 nodules (72.7%) were proven to be malignant by postoperative histopathological examination. On histopathological and Bethesda comparison, 93.75% sensitivity, 16.67% specificity, 75.00% PPV, and 50.00% NPV were observed (P <0.001). Concordence between Bethesda classification and TIRADS scoring system of USG guided FNAC of the lesions showed very good association in both benign (84.7%) and malignant (86.3%) lesion (p < 0.001).
Conclusion: The thyroid ultrasound report using the TIRADS criteria has a good concordance with the Bethesda cytology findings using USG guided FNAC. Correct interpretation by the two diagnostic modalities helps the clinician to stratify the thyroid nodules and reduce the risk of unnecessary invasive procedures in patients with low TIRADS score (TIRADS I AND 2) and nodules with high TIRADS score (TIRADS 4 and 5) should undergo USG guided FNAC and if Bethesda categories were suspicious of carcinoma or carcinoma should undergo surgery

Correlation of histopathology with risk of malignancy prediction by Assessment of Different NEoplasias in the adneXa (ADNEX) model from the International Ovarian Tumor Analysis (IOTA) group

Dr. Akhila J, Dr. Uma K

European Journal of Molecular & Clinical Medicine, 2023, Volume 10, Issue 2, Pages 1226-1234

The aim of the present study was to determine the specificity, sensitivity and accuracy of the predictors of ADNEX for risk stratification in different adnexal tumour histology.
Methods: It was hospital based observational Prospective Study in the Department of Pathology, Akash Institute of Medical Sciences and Reasearch centre, Devanahalli and cases of tubo-ovarian lesions by salphingo-oophorectomy/ovariectomy with or without hysterectomy. Total cases of tubo-ovarian lesions by salphingo-oophorectomy /ovariectomy with or without hysterectomy in last year were 146 out of total histopathogical biopsies 3101 at our centre AIMS&RC. So prevalence of tubo-ovarian lesions in last year was 4.7%. Out of which, 119 were non-neoplastic and benign cases (3.54%) and 27 were malignant cases (0.87%). The Prospective single centre study was done from 1st April 2021 to 31st March 2022.
Results: Maximum number of percentage lies in the age group 31 years to 40 years. In this study of 77 women, maximum were premenopausal 72.73% (56) followed by perimenopausal 7.79% (6) and post-menopausal 19.48% (15). In the study of 77 women, 88.31% (68) of women presented with complaints of pain abdomen followed by mass per abdomen 2.60% (2). 9.09% (7) presented with bleeding problems.
Conclusion: It can be inferred that the ADNEX model can be used as a good alternative to subjective assessment in the estimation of risk of malignancy of adnexal masses. It has the potential to change management decisions for women with an adnexal tumor. This could impact considerably on the morbidity and mortality associated with adnexal pathology.

PECULIARITIES OF LARYNGEAL ULTRASOUND IN DIAGNOSIS OF DYSPHONIA

Kudrat Mengkobilovich Salomov, Shavkat Ergashevich Amonov, Nigora Abdumalikovna Rasulova, Dodar Rahimovna Djabbarova, Habibullo Nasratullaevich Adullaev, Firuza Bahtiyorovna Nurmukhamedova

European Journal of Molecular & Clinical Medicine, 2023, Volume 10, Issue 1, Pages 3277-3285

Diagnosis and treatment of diseases of the larynx remains one of the most difficult tasks of otorhinolaryngology. Often, diseases of the larynx are manifested by impaired vocal function, that is, dysphonia. Voice pathology not only affects interpersonal relationships but also creates difficulties in professional activities. This is especially true for people of voice-speech professions, whose professional suitability and longevity depend on the quality of their voice.

A Prospective Observational Study To Predict Successful Supraclavicular Brachial Plexus Block Using Pulse Oximeter Perfusion Index

Dr. Buddhi Prakash Gautam, Dr. Abhilasha Thanvi, Dr. Kashmira Sharma, Dr. Anita Chouhan, Dr. Uma Dutt Sharma

European Journal of Molecular & Clinical Medicine, 2023, Volume 10, Issue 3, Pages 540-545

Upper extremity surgeries are being mostly done under regional anesthesia using supraclavicular brachial plexus block under ultrasound guidance. Subjective methodsto assess the block success take time and are not very reliable.
Aims- To use perfusion index values for prediction of successful ultrasound guided supraclavicular brachial plexus block.
Materials and methods- This prospective observational study was done on 70 patients who underwent upper limb surgery. Ultrasound guided supraclavicular block was given using 20 ml of 0.5% ropivacaine in all patients. Assessment of sensory and motor block was done at every 5 minute interval. The perfusion index was noted at baseline and at 5, 10, 15, 20, 25 and 30 minutes using separate pulse oximeters on index finger of both blocked and unblocked upper limbs. The perfusion index (PI) ratio was calculated as ratio of PI at 10 minutes and PI at baseline.
Results- There was increase in perfusion index (PI) and PI ratio in the blocked arm compared with the unblocked arm with statistically significant difference.
Conclusion- Perfusion index (PI) and PI ratio at 10 min are good predictors of success of supraclavicular block which can be used non invasively in all patients

A CLINICOPATHOLOGICAL STUDY OF WOMEN WITH ADNEXAL MASSES

European Journal of Molecular & Clinical Medicine, 2023, Volume 10, Issue 3, Pages 478-488

BACKGROUND: An adnexal mass is a common gynaecological problem. Hence evaluation of adnexal mass is of particular importance in gynaecological practice and often present diagnostic and management dilemma.The aims and objectives of the study were to find out different types of adnexal pathology clinically, correlation of clinical finding with histopathology, correlation of ultrasonography finding with histopathology.
METHODS: The study was carried in the Department of Obstetrics and Gynecology,Gandhi medical college  from 1st February 2019 to 31st January June 2021. This study was a hospital based observational study which included 150 patients . All cases underwent an ultrasound examination . Following surgery, specimens were sent for histopathological examination and the reports were correlated with pre-operative clinical and ultrasonography findings.

A comparative study between Johnson formula and Hadlock formula for estimating fetal weight in term gestation – At A Tertiary Care Institute

Siddhi Fuke , Kiran Patole , Abhijeet Patil .

European Journal of Molecular & Clinical Medicine, 2023, Volume 10, Issue 3, Pages 67-82

Background: The perinatal and maternal outcome grossly depends upon the fetal weight at term gestation. In urban setup, ultrasound is easily available for birth weight estimation. In rural setup USG are not easily available and clinical methods are still used for birth weight estimation as it don’t require any costly equipment and they are easy to use and give immediate estimation of expected birth weight.
Methods: It is a Hospital based observational study done between August 2019 to December 2021 conducted at the Department of Obstetrics and Gynaecology of Dr Vasantrao Pawar Medial College, hospital and research center, Nashik, Maharashtra. All subjects with singleton pregnancy with reliable gestation scan with no fetal anomalies were included.
Estimated fetal weight (EFW) was calculated by Johnson’s formula as clinical method and Hadlock formula using Ultrasound was used. EFW were compared with the actual birth weight.

Role of high-resolution ultrasound in rotator cuff tears: A cross sectional study

Praveen Kumar M, Arunkumar M, Jayaraja D, Praveen Kumar N, Joseph Selvasingh J

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 9, Pages 348-353

Dynamic evaluation of high resolution ultrasound is non invasive and no radiation. The real time nature of sonography requires personal interaction with the patient, often resulting in a more directed examination specific for each individual. The aim of this study was to assess the role of high resolution ultrasound in rotator cuff tears.
Materials and Methods: This is a hospital based cross sectional study in which all patients referred to the department of Radio Diagnosis (Chettinad health city) with clinically suspected rotator cuff injuries in a period of January 2015 – May 2016 were assesed. 30 patients referred to the department of Radio Diagnosis (Chettinad health city) with clinically suspected rotator cuff injuries in a period of 2 years were included according to the inclusion criteria.
Results: In our study, most of the patients with rotator cuff injuries presented with shoulder pain (46.7%), followed by decreased range of shoulder movements (26.7%), shoulder pain and stiffness (13.3%), stiffness (10%) and shoulder pain and weakness (3.3%). In our study USG had a sensitivity of 63%, specificity of 82%, PPV of 100%, NPV of 33.5%, diagnostic accuracy of 68% and kappa degree of agreement of 0.34. These results suggest that USG is less reliable in detecting rotator cuff tears than previously reported and a positive sonographic reading is more reliable than a negative one.
Conclusion: No single test had both a high specificity and a high sensitivity, therefore diagnostic accuracy of shoulder examination is overestimated, and that these exams are only rarely useful to differentiate rotator cuff tears. USG is less reliable in detecting rotator cuff tears than previously reported and a positive sonographic reading is more reliable than a negative one.

Wrist Joint Pain: A Clinical and Radiological Correlation

Sandeep Madineni, Mandepudi Geethika, Subhashreddy Doni, G. Harshavardhan Reddy, G. Naga Vaishnavi, V.N.S. Madhavi Latha, T. Ganesh

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 7, Pages 2656-2667

Background: Wrist discomfort is frequent in Orthopedic OPD. Computers, phones, laptops, and other electronics aggravate wrist pain. Treatment requires accurate diagnosis. Diagnostic imaging confirms. Ultrasound, MRI, and X-ray are employed. Critical imaging. Sonography and physical exam solve diagnostic problems. Real-time ultrasound is cost-effective for wrist imaging. Ultrasound imaging has improved for wrist joint diseases. It's cheaper than other methods. Cost and availability make wrist ultrasonography significant in our country. Ultrasound is the primary line of imaging for a patient with wrist joint pain. Use ultrasound along with X-rays and clinical exam to aid in speedy and decisive diagnosis, avoiding expensive investigative modalities. To describe USG image interpretation problems.
Material and Methods: In our study, a prospective analysis of 100 individuals who had wrist pain was included. Additionally, a pre-written consent is obtained. All patients got a complete clinical examination, a USG of the affected wrist with comparison to the other side, and an X-ray (PA & Lateral) of the affected wrist
Results: A wide range of pathologies, including anomalies of the local bones, joints, and soft-tissue structures including tendons, can cause the clinical manifestation of wrist pain. US can help identify the precise source of wrist pain.
Conclusion: For a case of wrist pain, a USG examination can be performed as the initial line of inquiry because it is affordable, real-time, and enables comparison with the contralateral side.

Prostate volume and lower urinary tract symptoms

Dr. Anil Huddedar, Dr. Abhijeet Katkar, Dr. Yogesh Jadhav, Dr. Asit Chawdhary, Dr. Atul Pawar

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 7, Pages 5754-5758

Background: Benign prostatic hyperplasia (BPH) is a common progressive disease in the male aging population. The present study assessed relationship between prostate volume and lower urinary tract symptoms.
Materials & Methods: 80 male patients of lower urinary tract symptoms were selected and International Prostate Symptom Score (IPSS) was used for the evaluation of benign prostatic hyperplasia (BPH). All underwent ultrasonography of lower abdomen and the prostate volume of each patient was estimated.
Results: Age group age group 30-40 years had 8, 40-50 years had 11, 50-60 years had 26, 60-70 years had 22 and >70 years had 10 patients. The difference was significant (P< 0.05). Prostrate volume (in cc) 20-30 was seen among 15, 30-40 cc in 22, 40-50 cc in 16, 50-60 cc in 5, 60-70 cc in 12, 70-80 cc in 7 and 80-90 cc in 3 patients. The difference was significant (P< 0.05). IPSS revealed mild cases in 26, moderate in 34 and severe in 20. Prostrate volume 20-30 cc had 5, 10 and 0, 30-40 cc had 6, 11 and 5, 40-50 cc had 5, 5 and 6, 50-60 cc had 1, 3 and 3, 60-70 cc had 3, 1 and 8, 70-80 cc had 4, 2 and 0 and 80-90 cc had 2, 1 and 0 respectively.
Conclusion: Males with severe burden of lower urinary tract symptoms (LUTS) often have measurable decrements in overall health-related quality of life. IPSS total score and prostate volume showed a significant positive relationship.

Accuracy of Ultrasound Elastography in Characterization of Breast Lesions

Vadlapally Karuna, G. Telma Priyanka

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 7, Pages 791-804

Background: The paper reviews elastography's importance in distinguishing benign from malignant breast lesions. Breast cancer accounts for 27% of all cancers among women in India, according to NICPR. Breast lumps can be benign cysts or malignant lesions.4Incidence rises in early 30s and peaks in 50s-64s.
Martial and Methods: This prospective, cross-sectional, diagnostic study was done at NRI General Hospital, Guntur, and Andhra Pradesh, India. 82 individuals were excluded from ultrasound electrography using PHILIPS AFFINITY 70. November 2019-October 2021 was the study's duration.
Results: 53 of 82 research participants had benign lesions. USG found 29 women with malignant lesions. HPE found 45 benign and 27 malignant tumours. In the current study, most women had a bump and mastalgia. Malignancies often cause nosebleeds. Benign instances show mastalgia, lump, swelling. 13 asymptomatic patients. 2 had malignant lesions. 9 were benign. One case of malignant nipple ulcer was found.
Conclusion: Dense breasts reduce mammogram detection of breast cancer. Ultrasonography shows dense glandular tissue as hyperechoic, but breast tumours are hypoechoic and easily recognised. Ionizing radiation limits mammography's age and frequency. Ultrasound elastography is risk-free.

Ultrasound guided unilateral erector spinae blockade in open cholecystectomy in COVID-19 era

DR ANURADHA SEN, DR SACHIN KUMAR GUPTA, DR SMRITI ANAND, DR MANDEEP KAUR

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 4, Pages 2497-2505

Background: The erector spinae plane (ESP) blockade acts as a potent unilateral analgesic technique. The block is performed by injecting local anaesthetic drug in the plane between the erector spinae muscle and the vertebral transverse process, with its effect due to diffusion of the local anaesthetic into the paravertebral space through spaces between the adjacent vertebrae. It is a relatively safe and easy technique as compared to the thoracic epidural because our target in ESP blockade is the transverse process, which is identified easily and is distant from neural or major vascular structures and the pleura. Aim of the study: To assess the analgesic effect of ultrasound guided unilateral erector spinae blockade in open cholecystectomy Material and methods:We present a case series of ESP blockade under ultrasound guidance in nine patients scheduled for open cholecystectomy because surgeons chose to avoid laparoscopic surgery due to the increased risk of COVID-19 infection due to intraperitoneal aerosol generation. Results: All patients with postoperative ESP blockade maintained an NRS pain score of 03/10 for 24 h, except for those requiring emergency analgesia. The pain relief was excellent in all our patients and there were no complaints of nausea, vomiting. Conclusion: ESP blockade is proving to be a successful technique for intraoperative and postoperative analgesia.

CORRELATION OF SPLENIC WEIGHT WITH THE WEIGHT AND SEX OF AN INDIVIDUAL – A CROSS SECTION STUDY

Ravi Shankar G, Roopa C R, Mohammed Ismail, Shilpa D

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 4, Pages 1258-1263

Background:The normal weight of the spleen various from 80 – 300 gm various tcxt books describe the measurement of splenic weight but not it’s correlation with the weight of an individual. As per the data available there are few studies done, correlating the splenic weight and weight of an individual. Clinically weight of the spleen is more significant. Hence this study has been taken up with the criteria of ultrasonographic measurement of splenic weight and its correlation with weight of an individual. Objective: To estimate splenic weight in correlation with the weight and sex of an individual.
Materials and Methods: The study was conducted in department of Radio diagnosis, Raichur Institute Medical Sciences and Navodaya Medical College Hospital, Raichur, 500 individuals were selected for the study based on inclusion and exclusion and criteria. Splenic dimensions were measured with the help of Ultrasound and Splenic weight was calculated with the help of formula. Weight of the individual was measured in Kgs with the help of weighing machine and statistical analysis was done using formulas.
Results: The weight of the Spleen increases proportionately with increase in weight of individual.(F = 5.835, P<0.001) in Males, (F = 2.697, P = 0.02) in Females.
Conclusion: The relation between Splenic weight and weight of an individual is significantly positive.

CLINICO-RADIOLOGICAL CORRELATION OFSHOULDER PAIN

Dr.KothaVinay Kumar Reddy, Dr.Madan Mohan Babu L, Dr. Suresh A, Dr.Shubham Gupta, Dr.Devamani VKH Chalavadi

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 4, Pages 60-69

Background - Shoulder pain is one of the commonest conditions encountered in our
orthopedic department. Accurate diagnosis is a must before undertaking any treatment. Since
clinical diagnosis cannot make an accurate diagnosis, radiological investigation is necessary
to know the exact cause of shoulder pain. There are a wide range of invasive and noninvasive
modalities that can be used to investigate these patients. Ultrasound examination is a
highly specific and sensitive modality in comparison with MRI. High-resolution real-time
USG has shown to be a cost-effective means of investigation of rotator cuff pathologies. With
recent advances with USG, results of imaging of shoulder joint pathologies are as similar or
in some cases more precise in the diagnosis than MRI.
Methods - Prospective analysis of 52 patients presenting with shoulder pain were included in
our study. A pre-formed written consent is also taken. All patients underwent a thorough
clinical examination, USG of the affected shoulder with comparison of the opposite side and
MRI of the affected shoulder for comparison.
Results - Ultrasound is equivalent in detection of rotator cuff tears in comparison with MRI.
MRI outscores ultrasound in detection of labral tears, cartilaginous lesions and subtle bony
lesions. USG examination can be used as the first line of investigating a case of shoulder pain
as it is inexpensive, real time and allows for comparison with the opposite side. MRI can be
used as a confirmatory tool.

TO DETERMINE THE EFFICACY OF ULTRASOUND IN THE DIAGNOSIS OF NECK SWELLINGS

Dr SeemaPandey, Dr Neetu Singh, Dr Mahendra Mehta, Dr Sunil Sanga

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 4, Pages 1264-1271

Aim: To determine the efficacy of ultrasound in the diagnosis of neckswellings.
Methods: This research comprised 50 instances with clinically evident swellings in the neck area. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of ultrasonography diagnosis were assessed for each group of neck swellings. The sensitivity analysis for such a tiny number is invalid since there were only three congenital swellings.
Results: Our research comprised patients of various ages, with a minimum age of 25 days and a maximum age of 82 years, with a mean age of 37.5 years. In our research, 15 (30%) of the patients were men, whereas 35 (70%) were girls.  According to the research, about two-thirds (32) of neck swellings were solid, 5 were cystic, and 13 swellings contained both solid and cystic components. In our investigation, 64% of clinically firm swellings were determined to be solid, whereas the rest were either completely cystic or mixed in nature. This research found that the Sensitivity, Specificity, PPV, and NPV of the US for inflammatory swellings are 87 percent, 97 percent, 95 percent, and 92 percent, respectively. The sensitivity analysis of clinical diagnosis and ultrasound diagnostic for inflammatory swellings.The sensitivity of US in identifying malignant lesions of the neck in 50 patients with neck swellings was 87 percent in this research, with a specificity of 99 percent, PPV 93 percent, and NPV 97 percent.
Conclusion: US can tell the difference between solid and cystic neck swellings, as well as malignant and benign neck swellings. It may detect thyroid, salivary gland, and lymph node lesions, as well as differentiate between abscess and cellulitis.

DIAGNOSTIC ACCURACY OF ADNEXAL MASSES THROUGH MAGNETIC RESONANCE IMAGING IN CORRELATION WITH HISTOPATHOLOGY

Dr. Kushpreet Kaur, Dr. Priyank Dwivedi, Dr. Sheetal Singh, Dr.Amlendu Nagar, Dr Saba Alvi .

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 721-741

Introduction:. The present study was conducted with an aim to assess the role of MRI for evaluation of adnexal masses and to find out the diagnostic accuracy of MRI in the diagnosis of adnexal masses against the gold standard test ‘histopathology’.
Materials and Methods: This is a prospective comparative study conducted in the Department of Radio Diagnosis, Index medical college hospital and research centre.50 women were taken in our study. These patients were first referred for ultrasonography with history of adnexal masses from gynaecological department. The magnetic resonance imaging was done using 1.5 Tesla MRI machine with patient in supine position.Then the lesion sample was taken and sent for histopathological examination. The results obtained on the MRI were evaluated against the histopathology results and the sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy of MRI was calculated.
Results: Out of 50 patients, 33 (66%) adnexal masses were benign, 15 (30%) were malignant and 2 (4%) were inconclusive on ultrasonography, 35 (70%) adnexal masses were benign, 15 (30%) were malignant on magnetic resonance imaging. 37 (74%) adnexal masses were benign, 13 (26%) were malignant on histopathology. The sensitivity of MRI in the diagnosis of malignant / benign adnexal masses against the histopathology was found to be 92.31%, specificity was 91.89%, positive predictive value was 80.00%, negative predictive value was 97.14% and diagnostic accuracy was 92.00%.
Conclusion: Ultrasound is unable to differentiate adnexal masses into malignant and benign in some cases and gives inconclusive results. While MRI provides better spatial and contrast resolution in delineation of the anatomical structures as well as characterization of pathological lesions. It is highly accurate in identifying the origin of a mass, characterization and staging and helps in the treatment planning. These parameters have been found quite in agreement with the findings of histopathology

Ultrasonographic correlation of placental thickness in third trimester with fetal parameters, birth weight and fetal outcome

Dr. Nikhil Arora, Dr. Sahil Arora, Dr. Yashaswi Sharma, Dr. Navkiran Dhanota, Dr. Priyanka Arora, Dr. Sanjeev Sharma

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 2, Pages 72-77

Introduction: Despite careful antenatal surveillance involving scrupulous examination, an issue of
considerable disappointment is that a majority of low-birth-weight infants are not diagnosed until
delivery. Low birth weight infants are susceptible to hypoxia and fetal distress, long-term handicap, and
fetal death.
Objectives: The present study will be undertaken in our institution to study the correlation of placental
thickness, measured at the level of the umbilical cord insertion, with the ultrasonographic gestational age
in normal women and fetal weight and outcome.
Methods: Present study was a single centric, observational, cohort, follow up, hospital-based study in
which 100 pregnant women who will come for ultrasound in third trimester during the study period was
recruited in the study. The relationship between placental thickness with fetal parameters, birth weight
and fetal outcome at delivery was investigated in this study. Correlation between placental thickness with
the fetal parameters, average gestational age, gestation at delivery, neonatal birth weight & APGAR
score, and placental weight was investigated during this study.
Results: Significant positive correction of placenta thickness was found with the gestation age, estimated
and actual fetal birth weight, and placenta weight. APGAR score showed negative correlation with the
placenta thickness. Positive correlation of placenta thickness was also found with the Biparietal diameter
(BPD), Head Circumference (HC), abdominal circumference (AC) and Femur length (FL).
Conclusion: Ultrasonography serves a significant role in estimating foetal weight, which is a crucial
component of prenatal care. Because of its linear association, placental thickness evaluated at the level
of umbilical cord insertion can be utilised as a reliable sonographic indication in the evaluation of. As a
result, it can be utilised as a secondary sonographic method for determining foetal weight.

Comparative study between pigtail catheter drainage and needle aspiration in management of liver abscesses

Dr. Vijaylakshmi GN, Dr. Niyaz Ahmed, Dr. Shrinidhi B Joshi

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 2, Pages 2081-2085

Liver abscess is a disease of frequent occurrence. Treatment modalities include both medical and surgical. However surgical drainage is the mainstay of treatment. With advent of ultrasound, percutaneous aspiration is becoming popular. Subjects from hospitals were grouped into those who underwent percutaneous aspiration and those who underwent pigtail catheter insertion. Both the groups are compared with the parameters like duration of hospital stay, duration to achieve symptomatic relief, duration of IV antibiotics required. A total of 106 subjects were studied. 52 of them underwent repeated percutaneous aspiration. 54 of them underwent pigtail catheter insertion. It is observed that pigtail catheter insertion is a better modality for larger abscess when compared to percutaneous aspiration in terms of duration of hospital stay, need for iv antibiotics and duration to achieve symptomatic relief.

Correlation of Splenic Weight with the Weight and sex of an Individual – A Cross Section study

Ravi Shankar G, Roopa C R, Shilpa D

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 11732-11736

Background:The normal weight of the spleen various from 80 – 300 gm various tcxt
books describe the measurement of splenic weight but not it’s correlRtion with the
weight of an individual. As per the data available there are few studies done, correlating
the splenic weight and weight of an individual. Clinically weight of the spleen is more
significant. Hence this study has been taken up with the criteria of ultrasonographic
measurement of splenic weight and its correlation with weight of an individual.
Objective: To estimate splenic weight in correlation with the weight and sex of an
individual.
Materials and Methods: The study was conducted in department of Radio diagnosis,
Raichur Institute Medical Sciences and Navodaya Medical College Hospital, Raichur,
500 individuals were selected for the study based on inclusion and exclusion and
criteria. Splenic dimensions were measured with the help of Ultrasound and Splenic
weight was calculated with the help of formula. Weight of the individual was measured
in Kgs with the help of weighing machine and statistical analysis was done using
formulas.
Results: The weight of the Spleen increases proportionately with increase in weight of
individual.(F = 5.835, P<0.001) in Males, (F = 2.697, P = 0.02) in Females.
Conclusion: The relation between Splenic weight and weight of an individual is
significantly positive.

ROLE OF HIGH FREQUENCY ULTRASOUND WITH COLOUR DOPPLER IN DIAGNOSIS OF ACUTE SCROTAL PAIN

Dr. Nirmal Kumar Mittal,Dr. Bharti Verma,Dr Pankaj Gupta,Dr. Renu Goindani

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 2, Pages 2846-2849

Background & Method: The aim of this study is tostudy the role of high frequency ultrasound with colour Doppler in diagnosis of acute scrotal pain. Ultrasound of scrotum is performed with patient in supine position & the scrotum supported by towel placed between things. A large amount of gel is used to minimize pressure on the scrotal skin. High frequency linear array transducer is used for performing study. Each hemiscrotum is scanned in longitudinal & transverse planes.
 
Result: The most common presenting complaint of the patient was swelling in the scrotal region (49.3%). Many patients had more than one symptoms. Extratesticular lesions was more common in the study (52.6%) than the testicular lesion (20.6%) The left scrotal sac was more commonly affected (42%) in the study. Bilateral   involvement is seen in (25.4%) of cases.
 
Conclusion: High frequency ultra sound combined with colour Doppler remains an accurate, rapid & safe diagnostic tool in imaging scrotum. High frequency ultrasound helps to distinguish intra testicular from extra testicular lesions. Improvement in resolution permitted greater confidence in characterization of lesions. Most common clinical presentation was swelling 49.3% followed by pain (34%). Most of the patients had unilateral involvement of left hemi scrotum (42%) in the study.

A study of correlation of ultrasound, MRI and arthroscopic findings in diagnosing rotator cuff pathology

Dr. Yunus Salim CM, Dr. Muni Sankar Reddy M

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 2, Pages 1307-1315

Background: The shoulder arthroscopy is the gold standard of reference in most of the shoulder pathologies including Rotator cuff tears. However, it is an invasive surgical procedure with associated risks of surgery and anaesthesia. The objective of the present study is to find out how accurately the rotator cuff pathologies can be diagnosed by these imaging tests.
Aims and Objectives: To compare the Ultrasonography, MRI findings with the Arthroscopic findings of Rotator cuff pathology of the shoulder.
Materials and Methods: All patients in whom the history and clinical examination is suggestive of Rotator cuff pathology were included in the study. Patients were evaluated using high resolution Ultrasound (HRUS) Philips HD-11, Germany and 1.5-Tesla MRI [1.5 Tesla, GE, Excite HD and USA]. Ultrasonographic and MRI examination is performed by a single radiologist experienced in musculoskeletal ultrasonography and MR Imaging. A Real time high resolution USG imaging and MRI of the shoulder was performed in a standardized fashion and subsequently with therapeutic or diagnostic arthroscopy on the symptomatic shoulder. Results were analyzed.
Results: Considering arthroscopy as the final gold standard of investigation, out of the 24 patients studied, five (20.8%) had rotator cuff tendinosis/tendinopathy, four (16.6%) had PT RCT, twelve (50%) had FT RCT while the remaining three (12.6%) had normal rotator cuff. The average delay between the MRI examination and arthroscopic surgery was 6 days (range 0-27 days) but in one case, it was as long as 117 days. A total of five (20.8%) patients were in the age group < 40 years while another five (20.8%) were between 40-50 years age group. A majority of eleven (45.8%) patients were between 50-60 years old while three (12.6%) were above 60 years.
Conclusion: It should be noted that following USG of the shoulder performed by a dedicated radiologist, MRI offers little additional value, with regard to the detection of rotator cuff tears.

Assessment of awareness towards hypertension management in general practitioners

Dr. Ratandeep Lamba

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 2121-2125

Background: Hypertension is a common chronic disease worldwide and a major risk
factor for cardiovascular disease. The present study was conducted to assess awareness
towards hypertension management in general practitioners.
Materials & Methods: 125 general practitioners of both genders were enrolled. A
questionnaire was prepared and was distributed among all participants and response
was recorded.
Results: Out of 125 subjects, males were 65 and females were 60. The number of
readings of blood pressure was 1 by 15%, 2 by 40% and 3 by 35%. Cuff placement
covering 2/3 of arm at heart level was recommended by 78%. Preferred position of
patient was sitting by 48%, supine by 32% and standing and supine by 20%. The
difference was significant (P< 0.05). Investigation preferred by GP were RBS by 85%,
ECG by 96%, ultrasound of abdomen by 42%, serum creatinine by 85%, lipid profile
by 87%, serum potassium level by 70% and urine examination by 67%. The difference
was significant (P< 0.05).
Conclusion: Most of the general practitionershad sufficient awareness regarding
techniques and symptoms of hypertension.

Analysis of Clinico-radio-pathological Features and Biological Behavior of Breast Cancer in Young Indian Women: An Institutional Based Study

Shivendra Kumar Chaudhary, Pragya Sinha

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 4, Pages 2720-2726

Background: Among women, incidence rates for breast cancer significantly exceeded
those for other cancers in both transitioned and transitioning countries, it remaining as
a remaining as most commonly diagnosed cancer and the prominent cause of cancer
death in women worldwide. The present study was conducted to assess Clinico-radiopathological
Features and Biological Behavior of Breast Cancer in Young Indian
Women.
Materials and Methods: A prospective descriptive study was done among women aged
less than 40 years diagnosed with breast cancer. In patients with suspicious clinical or
ultrasound findings or if biopsy yielded malignancy, digital mammography was
performed. All the BI-RADS 4 and 5 lesions and few of the BI-RADS 3 lesions were
biopsied, and samples were sent for histopathology (HPE) and immunohistochemistry
(IHC) examinations. The data was collected on Microsoft Office Excel 2013 and
statistical analysis was performed using IBM SPSS version 21(Illinois, Chicago). P value
<0.05 was considered significant.

Ultrasound Guided Quadratus Lumborum Versus Transversus Abdominis Plane Blocks For Postoperative Pain Control In Lower Abdominal Surgeries

Zainab Hamed Sawan, Sanaa Ahmed El-Tohamy, Mohamed Ali Abd-El Aziz, Sara Osman El- Shamaa

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 3, Pages 4936-4946

Background: Acute postoperative pain is a major problem, leads to undesirable outcome if not controlled probably. Therefore, appropriate management of acute perioperative pain using multimodal or balanced analgesia is crucial. The aim of the study was to compare between ultrasound guided quadratus lumborum block (QLB) and transversus abdominis plane (TAP) block as postoperative analgesia in lower abdominal surgeries. Patients & Methods: Thirty patients, aged from 21 to 50 years, ASA physical status I or II, scheduled for unilateral lower abdominal surgeries under general anesthesia were randomly divided into two equal groups of fifteen each. QLB group: patients received unilateral QLB block with 30 ml of 0.25% bupivacaine and TAP Group: Patients received unilateral TAP block with 30 ml of 0.25% bupivacaine. All patients in both groups were assessed for: Postoperative Visual analogue score (VAS), time to 1st rescue of analgesia, sensory block assessment (onset, level). In addition, total nalbuphine consumption in the first postoperative 24h and patient satisfaction were also recorded. Results: VAS was significantly higher in patients received TAP block. Patients received QLB showed rapid sensory loss with higher sensory block level in comparison to TAP block group. Time to 1st rescue of analgesia, was delayed in patients received QLB, so, this group showed longer duration of analgesia with higher satisfaction score than TAP group. In addition, the total nalbuphine consumption was higher in the first 24 hours in TAP block group compared to QLB group. Conclusion: The recently introduced QLB, may be a good option for postoperative pain relief after lower abdominal surgery with reduction of opioid consumption, prolonged duration of analgesia, and higher patient satisfaction compared to transversus abdominis plane block. We belief that if US guided QLB is performed by experienced hands; it is safe and effective technique for postoperative analgesia.

Role of MRI and high resolution ultrasound in rotator cuff tears

Dr. Peerzada Ziaulhaq, Dr. Najeeb Tallal Ahangar, Dr. Asif Majid Wani, Dr. Shabir Ahmad Bhat

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 2, Pages 2807-2820

Background: The shoulder joint is a ball and socket variety of joint with wide range of movements in multiple planes where stability is compromised for mobility. The muscles and tendons are subjected to severe strain resulting in tears. Rotator cuff disease is one of the most common causes of shoulder pain. In addition to history and physical examination, several radiological techniques have been used to detect tears of the rotator cuff. Each has limitations and no clear consensus on the optimum diagnostic study has emerged. The radiological diagnosis of rotator cuff tears has traditionally been performed with arthrography and more recently with non-invasive techniques like ultrasonography and MRI.
Aims and objectives: Evaluation of role of MRI in rotator cuff injuries, evaluation of role of high resolution ultrasound in rotator cuff injuries. Correlation of clinical and high resolution ultrasound findings with MRI findings.
Materials and Methods: In our study we took over the analysis of 32 patients with clinically suspected rotator cuff injuries were subjected to undergo USG and MRI after thorough history taking and clinical examination. USG was carried out on IU22 Philips machine using a high frequency transducer of 5-17 MHz. The rotator cuff tendons, muscles, ACJ, joint cavity and bursae were examined in various positions. Dynamic examination of shoulder were also carried out for impingement. MRI was performed on 1.5 Tesla MRI scanner, using a dedicated surface coil for shoulder.

Prevalence Of Gallstone In Relation To Age, Sex And Body Mass Index In Tikrit City

Meqdam A. Khalaf; Abdulhadi M. Jumaa; Ammar L. Hussein

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 3, Pages 418-423

gallstones are common diseases in many countries of the world , and incidence rate may reach about 20 % .Most cases of gallstones occur in females , the incidence rate may reach four times to one in comparison between women and men , mainly in fatty , fertile , age of forty female , gall stones are rare before age of 20 years ,but; may occur at any age . many cases are not diagnosed because they do not cause any signs or symptoms , and thus can only be diagnosed accidently by routine abdominal ultrasound.
The aim of study is to evaluate the relationship between age,sex and body mass index as risk factors for gallstone.
a cross sectional study was conducted in Tikrit city during the period from early of May to the end of October 2019 . 468 were enrolled in present study , and only 95 patients were diagnosed as a case of gallstone (29 male , 66 female). All patients attending private ultrasound clinic with different complains, data was collected by using certain questionnaire.
The results showed that, There was highly significant statistical relationship (P – value ≤0.05) between body mass index mean in both gallstone cases(26.628±5.808) and, in cases without gallstone(22.225±1.316). In the present study there was high statistically significant relation(P- value ≤ 0.05) between body mass index measurement above 25(31.97727273± 3.747859149) and measurement below 25(21.85882353± 1.616313889) in patients with gallstone.
The present study conclude that , Body mass index more than 25 considered as an important risk factor for gallstone.

Program For Diagnosing The Degree Of Urodynamic Disorders And Kidney Functions And Determining Tactics Of Managing Children With Obstructive Uropathies.

Mavlyanov Farkhod Shavkatovich; Mavlyanov Shavkat Khodzhamkulovich; Shirov Timur Furkatovich; Khayitov Ulugbek Khudzhakulovich

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 3, Pages 2546-2554

Background: The objective of the study is to develop a program of scoring for determining the degree of impairment of urodynamics and the preservation of renal function in children with obstructive uropathy on the basis of data from ultrasound - Doppler studies.
Methods: The work is based on the results of ultrasound and Doppler examination of 484 children with congenital obstructive uropathy. In accordance with the obtained data, a point assessment of the degree of impairment of urodynamics and preservation of renal function was carried out in 60 children with obstructive uropathies (30 children with congenital hydronephrosis and 30 children with congenital ureterohydronephrosis).
Results: Analysis of ultrasound and Doppler studies in congenital obstructive uropathy in children by comparing the data, depending on the severity and level of obstruction, revealed 3 degrees of congenital obstruction of the upper urinary tract in children. A comparative study of the urodynamics and state of the renal parenchyma, depending on the degree of obstruction, established a close relationship between the indicators of the functional state of the renal parenchyma and the degree of dilatation and disorders of the urodynamics of the upper urinary tract.
Conclusion: The developed program allows the safe and most informative methods to reliably determine the functional state of the renal parenchyma and the degree of urodynamic impairment in children with obstructive uropathy. Study Registration (ClinicalTrials.gov) ID NCT04605835.

Leukemia Recurrence Exclusively in the Breast after Stem Cell Transplant

Naziya Samreen; Shahrukh K. Hashmi; Amy Lynn Conners; Asha Bhatt; Katrina N. Glazebrook

European Journal of Molecular & Clinical Medicine, 2018, Volume 5, Issue 1, Pages 41-45

Introduction: Leukemic involvement of the breast is extremely rare but constitutes an oncologic emergency. Imaging findings of T-Cell acute lymphoblastic leukemia (T-ALL) recurrence in the breasts have not been previously described. Case Description: Patient is a 25 year old female who presented with symptoms of superior vena cava (SVC) obstruction secondary to a mediastinal mass status post biopsy demonstrating T-ALL, which was cluster of differentiation 3 (CD3) positive and B-cell lymphoma 2 (BCL-2), and 80% Ki-67 positive. She was treated with chemotherapy and post-treatment positron emission tomography/computed tomography (PET/CT) demonstrated resolution of mediastinal mass, with no evidence of distant disease. She underwent allogeneic hematopoietic stem cell transplant (HSCT) in first remission. Seven months post-HSCT, patient presented with a large area of tender swelling of both the breasts with biopsy demonstrating relapsed T-ALL. Radiologic findings showed bilateral breast masses on ultrasound and mammogram, which were hypermetabolic on PET/CT. Conclusions: Breast involvement in leukemia recurrence, a very rare entity, can present with palpable masses. Mammographic findings in leukemia can include masses or architectural distortion, they are typically hyperechoic on ultrasound, and can have marked uptake on PET/CT. Oncologists, primary care providers and radiologists should be aware of leukemia presentations in the breast for prompt referral for urgent management.