Online ISSN: 2515-8260

Keywords : Hypocalcemia

Early Predictive Factors of Hypocalcemia Following Total Thyroidectomy: A Hospital Based Study

Syed Mahmood Ayaz, Sohan B, Sajid Ibrahim Ali, Sachin Murukanahalli Basavaraju

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 302-309

Background: In thyroid surgeries, hypocalcemia is a very common complication mainly
because of the similar blood supply to both thyroid and parathyroids Objectives:
measurement of parathormone (PTH) during total thyroidectomy can identify at risk
patients of developing hypocalcaemia.
Materials and Methods: This is a Four-year prospective and cross-sectional study was
conducted in three hospitals i.e Study subjects in which all thyroidectomy patients 18
years or above will be screened for development of hypocalcaemia who met inclusion
criteria was taken up for study during the study period. The study is a time bound study
including all thyroidectomy cases done from October 2017 to August 2021 which
included a total of 62 patients.

A Study on Clinical Study of Infants of Diabetic Mother

Suraboina Satishkumar, Gajula Ravi, Janardhan Reddy Pulluru

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 10357-10364

Background:Recently, a number of publications have raised concern about the rising
prevalence of diabetes mellitus in Telangana. The International Diabetes Federation has
named Saudi Arabia among the top 10 countries with the highest prevalence of diabetes
Objective of the Study: To observe and evaluate the incidence and complications seen in
infants of diabetic mothers.
Materials and Methods: It is a prospective observational time bound study conducted
Yashoda Hospital, Telangana, India from December 2019 to November 2020. All live
babies born to mothers with GDM or pregestational DM were enrolled in study.
Maternal history and complications during labour were recorded. APGAR scores
assessed. Investigation for glucose estimation, PCV, serum calcium, serum bilirubin was
sent. Chest X ray was done in babies with respiratory distress. 2D ECHO, USG
abdomen, USG cranium were done in all babies after stablisation.
Results: 70 neonates were born to diabetic mothers. 2 IUD and 6 still born were
excluded from study and 62 neonates were evaluated. 2 neonates died.70.96% were
term babies and 29 % preterm. 40 infants (64.5%) were born to GDM mothers, 20
(32.3%) to mothers with type 2 DM and 2(3.2%) to type 1 DM. 16.2% were LGA while
12.9% were SGA. Hypocalcemia was seen in 4 neonates (6.7%). Hyperbilirubinemia
was seen in 4 (13.3%). Sepsis was seen in 8 neonates. CHDs were seen in 42.9%, most
common being ASD/PFO 21.3%. VSD was seen in 10.7%, PDA in 7.1% and septal
hypertrophy in 3.5%. One case had pyloric atresia and one had RDS. Association
between HbA1c levels and complications like macrosomia, hypoglycemia, congenital
anomalies was not significant in our study.
Conclusion: Neonates born to diabetic mother are at a high risk of developing
complications like hypoglycemia, hypocalcemia and cardiac defects.

Peculiarities Of The Hypofunction Of The Perthygroid Gland In Rats On The Morphological Formation Of Bone Tissue

Gulnoza O. Khidirova

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 3, Pages 3549-3565

This study is dedicated to the study of the effect of changes in the active energy of the parathyroid glands on the morphological tension of bone tissue formation. Experimental modeling of hypoparathyroidism in laboratory rats (n = 30) was carried out and the dynamics of morphological changes in the process of bone tissue ossification was analyzed. On the basis of the results of morphological methods of study, the dynamics of the formation of tubular bones was revealed, and the patterns of ossification of bone tissue against the background of hypoparathyroidism were also set. As a result of the study, it was shown that it differs from the usual histological picture of hypoparathyroid individuals in the zones of elevation, just the basal layer of chondrocytes are vacuolated. The emergence of young osteoblasts is oriented by the spaces; they are located according to the type of multidirectional architectonics


G. G. Joag; S. Y. Ingale; D. B. POTDAR; S.B Karanjkar; Kanvikar Reshmi

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 4125-4129

Present study is to assess the incidence of hypomagnesemia and hypocalcemia on day one and day four in neonates who are born in a tertiary care hospital of western maharashtra. Study done at KRISHNA Hospital, Karad. Children s who were born congenitally, and who met the eligibility criteria, were studied in the obstetric department of Krishna Hospital. 2.5 ml of cord blood was collected on day 1 of life in a plain bulb. On Day 1 of life, Hypocalcemia occurred in 0.5% of the 400 neonates studied. On Day 1 of life, Hypomagnesemia occurred in 1% of the 400 neonates studied. On Day 4 of life, Hypocalcemia occurred in 10.5% of the 400 neonates studied. On Day 4 of life, Hypomagnesemia occurred in 0% of the 400 neonates studied. No cases of Hypocalcemia with Hypomagnesemia occurred together at the same time either on Day 1 of life or on Day 4 of life.