Author : Ayaz, Dr. Md Rashid Ahsan Lodhi, Dr.Sayantaann Saha, Dr. C. R. Mallikarjuna, Dr. Asif
DYSFUNCTIONAL HDL- A DEVIL IN DISGUISE AS A PREDICTOR OF PROGRESSION OF CHRONIC KIDNEY DISEASE TO PROVIDE AN ALTERNATIVE TO URINARY ALBUMIN CREATININE RATIO [UACR] MEASUREMENT
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 3, Pages 1032-1039
cholesterol (HDL-C) are usually decreased. However, enough data assessing this relationship
is scarce in different literature commenting on kidney disease progression in patients having
chronic kidney disease
Aim: The present study was conducted to assess the correlation between the progression of
chronic kidney disease and serum high-density lipoprotein cholesterol levels to provide an
alternative to urinary albumin-creatinine ratio (UACR) measurement.
Methods:The present study assessed the relationship between the progression of chronic
kidney disease and serum high-density lipoprotein cholesterol levels in 542 subjects with
diagnosed chronic kidney disease. The primary and secondary outcomes assessed were a 50%
reduction in the estimated GFR (Glomerular Filtration Rate) from the baseline values or the
onset of end-stage renal disease (ESRD). The secondary outcomes assessed were the
development of end-stage renal disease.