Online ISSN: 2515-8260

Author : AS, Smiline Girija


ALLOGENEIC BONE MARROW TRANSPLANTATION IN MULTIPLE MYELOMA - A REVIEW OF LITERATURE

Deepthi Sogasu; Brundha MP; Smiline Girija AS

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 421-430

Multiple myeloma is a hematological malignancy of the plasma cells with evidence of bone marrow infiltration. It is accompanied with extramedullary plasmacytomas. There are a variety of possible treatment options, but this review focuses on allogeneic bone marrow transplantation for the treatment of multiple myeloma. Allogeneic bone marrow transplant is commonly known as stem cell transplantation. From the review, the results suggest that this can be used as a treatment option for fit young individuals as compared to older individuals. It also shows better results during the early stages relative to the later stages with poor prognosis. In conclusion, allogeneic bone marrow transplant can help treat multiple myeloma, but it depends on factors such as age, stage of cancer, fitness of the individual.

ROLE OF COMMONLY USED ASIAN SPICES IN BOOSTING IMMUNITY AGAINST INFECTIOUS AGENTS

Kethan Umakanth; Geetha RV; Smiline Girija AS; Lakshmi T

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 452-458

Spices are normally used for adding flavour to the food. Especially Asians use a variety of spices or spice blends to make food aromatic, hot, savoury and sweet. Spices not only add aroma to the food but also come with notable nutritional values and give a lot of health benefits. The spices that are typically used in Asian cuisine are Cinnamon, garlic, cloves, cumin, basil, star anise, galangal, ginger, coriander, turmeric, cilantro, pepper, ajowain etc. The main aim is to try and understand the role of commonly used Asian spices on boosting immunity against infectious agents. A large number of plants are used to treat many diseases as they possess antimicrobial activity. However, Challenges include Extinction or disappearance of a few indigenous varieties, Low productivity, Insufficient quantities of quality species and Poor product quality. Many people do not know the importance of spices and its effect on the immune system. There is a need to understand the traditional systems, to help visualise the future better . there is a necessity to link the past and the present of medicine. This can help in giving new directions for a better understanding of different diseases etc. As this is a review various other related research articles are acquired using the Search engines such as PubMed, google scholar, google Cochrane databases and MESH. Their data is taken as the base for our study.

LESSONS LEARNT FROM THE COVID-19 PANDEMIC IN ITALY

Apurva Choudhary; Smiline Girija AS

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 467-475

The spread of coronavirus disease 2019 (COVID 19) reached pandemic world-wide especially in Italy
from early March 2020. Many factors were under discussion among public health experts for the
exorbitant mortality rate in Italy than other countries. A coordinated global response was desperately
needed to prepare health systems to meet this unprecedented challenge in Italy. This review illustrates
predictions, chronic comorbidities, effects of COVID 19 on Italian health system. Covid disease affecting
the elderly population with co-morbidities, the same was associated in the mortality rate among elder
population in Italy in a greater rate. The mortality rate in Italy was also higher due to the asymptomatic
cases not being tested and isolated with initial screening. The most serious outcome of COVID 19
pneumonia was recorded among the population in Italy. Exhausted number of ICU’s beds, ventilators and
respirators revealed their un-preparedness for the covid-19 pandemic. This review thus focuses on the
various factors to be considered in future pandemics by analyzing the covid - 19 pandemic in Italy.