Online ISSN: 2515-8260

Treatment Of Cervical Cancer In Fertilized Women

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Navruzova V.S.1 , Yuldasheva N.Sh.2 , Navruzova R.S.3 , Nabieva U.P.4

Abstract

Malignant neoplasms of the reproductive system of women are the most frequent in the structure of oncological diseases. Their total total share is more than 38% in the structure of the overall incidence of malignant tumors. According to the WHO, 550 thousand cases of newly diagnosed cervical cancer (CC) and more than half of deaths from this pathology are registered annually in the world. In the Republic of Uzbekistan in 2012, 1323 patients with cervical cancer and 623 deaths from this disease were registered. In recent years, there has been an increase in the incidence among women of fertile age. Increasingly, the disease occurs between the ages of 28-45 years. In the Republic, about 60% of cervical cancer is detected in the I-II stage of the disease. Traditional anticancer treatment in the initial stages allows, in the overwhelming majority of cases, to save the patient's life, but leads to irreversible loss of fertility, which greatly reduces the quality of life of young women who have not previously realized reproductive function. Physiological and psychological consequences of infertility caused by the treatment of a malignant tumor are extremely negative. In addition to the fact of unrealized reproductive function, the majority of young patients in this group have depression of varying severity, stress disorders and sexual dysfunction. The peculiarities of morphogenesis and carcinogenesis of cervical tumors, high survival rates in early stages and an increase in the number of patients of reproductive age pose the task of oncogynecologists to improve the quality of life by preserving fertility. Based on these circumstances, it became necessary to develop and implement organpreserving surgery - radical abdominal trachelectomy. Cervical cancer is characterized mainly by the local spread of the tumor process. The transition of the tumor to the upper parts of the vagina, parametric tissue and sacro-uterine ligaments is most often observed. The growth of the tumor to the upper parts of the uterus is observed less often in 13-15% of cases. In the initial stages of cervical cancer, the tumor most often affects the transformation zone (), in 28-34% of patients the tumor is localized in the lower segment of the cervical canal, in 15% in the middle and in 2% in the upper segment. The middle and lower third of the vagina is affected in the common stages of cervical cancer and is rare.

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