Abstract: The effect of leadership on empowering human resources, (2). The influence of leadership on employee satisfaction, (3). The effect of empowering human resources on satisfaction, (4). Influence of satisfaction on employee performance, (5). The influence of leadership on employee satisfaction through empowering human resources. The population in this study was Konawe Regency Government Employees with the characteristicsof Civil Servants (PNS) in all OPDs within the Konawes Regency Government as many as 6,196 people. The sampling technique is stratified random sampling with a sample of 152 people. Data analysis technique to answer the problem in this research hypothesis is a quantitative analysis that is supported by Qualitative through two stages, namely statistical descriptive analysis and Structural Equation Modeling (SEM) analysis. The results showed that the relationship between leadership and human resource empowerment in this study was directly proportional; leadership had a positive and significant effect on employee satisfaction while Human Resources empowerment had a positive but not significant effect on job satisfaction. Job satisfaction has a positive and significant effect on employee performance has a positive but not significant effect on job satisfaction. Furthermore the empowerment variable does not significantly mediate the relationship between the leadership variable and job satisfaction variable