Online ISSN: 2515-8260

Serum brain natriuretic peptide levels in community acquired pneumonia and its comparison with CURB-65: A case series study

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Dr. Pramila Devi R, 2Dr. Raghavendra Mural, 3Dr. G Sreenath

Abstract

Background and Objectives: Community-acquired pneumonia (CAP) is the leading infectious cause of death in developed countries and remains the sixth most common overall cause of death1 . The clinical prognostic indices like pneumonia severity index (PSI) and CURB-65 have stood the test of time and are still being used in developing countries. But these are cumbersome and the observations may be examiner dependent. There arose a need for a reliable and quick laboratory-based index which could help in triaging the patient. Various inflammatory markers like CRP, Procalcitonin have been analyzed as potential candidates for triage because of the concept that the clinical severity of pneumonia is proportional to the inflammatory response. One important factor that could determine the severity is the extent of myocardial involvement. Hence the cardiac biomarkers were used in assessing the severity of pneumonia. The most useful of them are the natriuretic peptides and the most measurable of these peptides were BNP and NT- Pro BNP.

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