Aim: To evaluate the role of multidetector computed tomography in acute pancreatitis and severity of the disease using Modified CT Severity Index. Material and Methods: This prospective observational study was conducted in the department of Radio diagnosis, Imaging & Interventional radiology N.S.C.B Subharti Medical College, CSS Hospital, Meerut among 51 patients in any age group referred to the radiology department with clinical suspicion of acute pancreatitis for a period from October 2019 to August 2021.Detailed clinical history was taken from the patient relevant clinical examination done and serum urea and creatinine of the patient was checked.Severity of acute pancreatitis was analysed using MCTSI.